1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Angiotensin II (3-8), human

Angiotensin II (3-8), human 

Cat. No.: HY-P1515
Handling Instructions

Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Angiotensin II (3-8), human Chemical Structure

Angiotensin II (3-8), human Chemical Structure

CAS No. : 12676-15-2

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Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.

IC50 & Target

Angiotensin AT1 receptor[1]

In Vivo

Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances[1].

Molecular Weight








Sequence Shortening



Room temperature in continental US; may vary elsewhere


Please store the product under the recommended conditions in the Certificate of Analysis.

Animal Administration

Male Long Evans rats (350-450 g) (n=7) are given increasing bolus doses of AII (1.25, 12.5 and 125 pmol/kg) or human Angiotensin II (3-8) (0.125, 1.25 and 12.5 nmol/kg) in random order, in the morning or afternoon of the same experimental day. Injections are separated by at least 20 min to allow variables to return to baseline[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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