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Referencia número: HY-P1515

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Angiotensin II (3-8), human

Name: Angiotensin II (3-8), human
Brand: MedChemExpress
SKU: HY-P1515
Availability: PreOrder

2 Cited Publications

Revisión del cliente

Based on 2 publication(s) in Google Scholar

Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT₁ receptor.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 12676-15-2
Fòrmula: C₄₀H₅₄N₈O₈
Peso molecular:774.91

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Please store the product under the recommended conditions in the Certificate of Analysis.

Angiotensin II (3-8), human Chemical Structure

No. CAS: 12676-15-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- IC₅₀ & Target
- In Vivo
Chemical Information
Publications (2)
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Actividad biológica

Descripciòn

Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT₁ receptor.

IC₅₀ & Target

Angiotensin AT₁ receptor^[1]

Ver todos los productos específicos de isoformas Angiotensin Receptor :

In Vivo

Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 12676-15-2
Peso molecular 774.91
Fòrmula C₄₀H₅₄N₈O₈
Sequence

Val-Tyr-Ile-His-Pro-Phe
Sequence Shortening

VYIHPF
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Theranostics

Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis. [Abstract]

2021 Jul 25;11(18):8624-8639. PMID: 34522203
Eur J Pharmacol

Tanshinone I inhibits vascular smooth muscle cell proliferation by targeting insulin-like growth factor-1 receptor/phosphatidylinositol-3-kinase signaling pathway. [Abstract]

2019 Jun 15:853:93-102. PMID: 30878387

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Gardiner SM, et al. Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol. 1993 Sep;110(1):159-62. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Angiotensin II (3-8), human

2 Cited Publications

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Actividad biológica
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- IC₅₀ & Target
- In Vivo
Chemical Information
Publications (2)
Pureza y Documentación
Referencias

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Angiotensin II (3-8), human

Publications Citing Use of MedChemExpress (MCE) Angiotensin II (3-8), human

Ver todos los productos específicos de isoformas Angiotensin Receptor