1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Angiotensin III, human, mouse

Angiotensin III, human, mouse 

Cat. No.: HY-P1540
Handling Instructions

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Angiotensin III, human, mouse Chemical Structure

Angiotensin III, human, mouse Chemical Structure

CAS No. : 13602-53-4

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Description

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.

IC50 & Target

IC50: 0.648 nM (AT2R), 21.1 nM (AT1R)[1]

In Vitro

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively[1].

In Vivo

Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats[3].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

931.09

Formula

C₄₆H₆₆N₁₂O₉

CAS No.

13602-53-4

Sequence

Arg-Val-Tyr-Ile-His-Pro-Phe

Sequence Shortening

RVYIHPF

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Angiotensin III, human, mouse
Cat. No.:
HY-P1540
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Angiotensin III, human, mouse

Cat. No.: HY-P1540