1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Angiotensin III, human, mouse

Angiotensin III, human, mouse 

Cat. No.: HY-P1540 Purity: 99.80%
Handling Instructions

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Angiotensin III, human, mouse Chemical Structure

Angiotensin III, human, mouse Chemical Structure

CAS No. : 13602-53-4

Size Price Stock Quantity
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 90 In-stock
Estimated Time of Arrival: December 31
25 mg USD 150 In-stock
Estimated Time of Arrival: December 31
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.

IC50 & Target

IC50: 0.648 nM (AT2R), 21.1 nM (AT1R)[1]

In Vitro

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

931.09

Formula

C₄₆H₆₆N₁₂O₉

CAS No.

13602-53-4

Sequence

Arg-Val-Tyr-Ile-His-Pro-Phe

Sequence Shortening

RVYIHPF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (107.40 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0740 mL 5.3700 mL 10.7401 mL
5 mM 0.2148 mL 1.0740 mL 2.1480 mL
10 mM 0.1074 mL 0.5370 mL 1.0740 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Angiotensin III, human, mouseAngiotensin ReceptorInhibitorinhibitorinhibit

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Product Name:
Angiotensin III, human, mouse
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HY-P1540
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