1. GPCR/G Protein
  2. Angiotensin Receptor

Angiotensin III, human, mouse 

Cat. No.: HY-P1540
Handling Instructions

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively. Sequence: Arg-Val-Tyr-Ile-His-Pro-Phe;RVYIHPF.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Angiotensin III, human, mouse Chemical Structure

Angiotensin III, human, mouse Chemical Structure

CAS No. : 13602-53-4

Size Price Stock
5 mg USD 60 Get quote
10 mg USD 90 Get quote
25 mg USD 150 Get quote

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively. Sequence: Arg-Val-Tyr-Ile-His-Pro-Phe;RVYIHPF.

IC50 & Target

IC50: 0.648 nM (AT2R), 21.1 nM (AT1R)[1]

In Vitro

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively[1].

In Vivo

Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (UNaV), fractional excretion of sodium (FENa), and fractional excretion of lithium (FELi) in SD rat[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats[3].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0740 mL 5.3700 mL 10.7401 mL
5 mM 0.2148 mL 1.0740 mL 2.1480 mL
10 mM 0.1074 mL 0.5370 mL 1.0740 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

931.09

Formula

C₄₆H₆₆N₁₂O₉

CAS No.

13602-53-4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Angiotensin III, human, mouse
Cat. No.:
HY-P1540
Quantity:

Angiotensin III, human, mouse

Cat. No.: HY-P1540