2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase II inhibitor 8

Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase.

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Topoisomerase II inhibitor 8 Chemical Structure

Topoisomerase II inhibitor 8 Chemical Structure

CAS No. : 2493298-68-1

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Topoisomerase II inhibitor 8 Related Antibodies

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Description

Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].

IC50 & Target[1]

Topoisomerase II

0.52 μM (IC50)

Molecular Weight

312.30

Formula

C14H8N4O3S
CAS No.
SMILES

O=C(C1=CC=CO1)SC2=NN=C3N2C4=C(C=CC=C4)NC3=O
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Topoisomerase II inhibitor 8 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase II inhibitor 82493298-68-1Topoisomerase II inhibitor8Topoisomerase II inhibitor-8Topoisomeraseanti-proliferativecell cycleG2/M phaseInhibitorinhibitorinhibit

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