2493298-68-1
Chemical Structure
Topoisomerase II inhibitor 8
- CAS No.: 2493298-68-1
- Formula:C14H8N4O3S
- Molecular Weight:312.30
IUPAC Name: S-(4-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-1-yl) furan-2-carbothioate
InChIKey: OUCNSEMVYGJKCQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CO1)SC2=NN=C3N2C4=C(C=CC=C4)NC3=O
Biological Activity: Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].
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Topoisomerase II inhibitor 8 | Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase. | |||||||||||||||||||||
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Keywords