N6-Methyladenosine 5'-monophosphate disodium salt

Name: N6-Methyladenosine 5'-monophosphate disodium salt
Brand: MedChemExpress
SKU: HY-111926
Rating: 4.5 (1 reviews)

Cat. No.: HY-111926 Purity: 99.74%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a K_a value of 22 µM. N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor.

For research use only. We do not sell to patients.

N6-Methyladenosine 5'-monophosphate disodium salt Chemical Structure

CAS No. : 81921-35-9

Size	Price	Stock	Quantity
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 185	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 390	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a K_a value of 22 µM^[1]. N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor^[2].

IC₅₀ & Target

Ki: 22 Glycogen phosphorylase b^[1].
Adenylate kinase II^[2].

Molecular Weight

405.21

Formula

C₁₁H₁₄N₅Na₂O₇P

CAS No.

81921-35-9

Appearance

Solid

Color

White to light brown

SMILES

CNC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(O[Na])(O[Na])=O)O3)C=N2)=NC=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (246.79 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4679 mL	12.3393 mL	24.6786 mL
5 mM	0.4936 mL	2.4679 mL	4.9357 mL
10 mM	0.2468 mL	1.2339 mL	2.4679 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.74%

Select Batch:

Data Sheet (288 KB) SDS (252 KB)

COA (256 KB) HNMR (144 KB) RP-HPLC (168 KB) LCMS (106 KB)

Handling Instructions (2659 KB)

References

[1]. Groner Y, et al. 5'-Capping structures of Artemia salina mRNA and the translational inhibition by cap analogs. Eur J Biochem. 1976 Dec;71(1):281-93. [Content Brief]

[2]. Hai TT, et al. Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem. 1982 Oct;25(10):1184-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.4679 mL	12.3393 mL	24.6786 mL	61.6964 mL
	5 mM	0.4936 mL	2.4679 mL	4.9357 mL	12.3393 mL
	10 mM	0.2468 mL	1.2339 mL	2.4679 mL	6.1696 mL
	15 mM	0.1645 mL	0.8226 mL	1.6452 mL	4.1131 mL
	20 mM	0.1234 mL	0.6170 mL	1.2339 mL	3.0848 mL
	25 mM	0.0987 mL	0.4936 mL	0.9871 mL	2.4679 mL
	30 mM	0.0823 mL	0.4113 mL	0.8226 mL	2.0565 mL
	40 mM	0.0617 mL	0.3085 mL	0.6170 mL	1.5424 mL
	50 mM	0.0494 mL	0.2468 mL	0.4936 mL	1.2339 mL
	60 mM	0.0411 mL	0.2057 mL	0.4113 mL	1.0283 mL
	80 mM	0.0308 mL	0.1542 mL	0.3085 mL	0.7712 mL
	100 mM	0.0247 mL	0.1234 mL	0.2468 mL	0.6170 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.