1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
  2. Melatonin Receptor
    Drug Metabolite
  3. Ramelteon metabolite M-II-d3

Ramelteon metabolite M-II-d3 

Cat. No.: HY-103005S
Handling Instructions

Ramelteon metabolite M-II-d3 is the deuterium labeled Ramelteon metabolite M-II. Ramelteon metabolite M-II is the major metabolite of Ramelteon, with IC50s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2). Ramelteon is a selective melatonin agonist.

For research use only. We do not sell to patients.

Ramelteon metabolite M-II-d3 Chemical Structure

Ramelteon metabolite M-II-d3 Chemical Structure

CAS No. : 1246812-22-5

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1 mg USD 450 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Ramelteon metabolite M-II-d3 is the deuterium labeled Ramelteon metabolite M-II. Ramelteon metabolite M-II is the major metabolite of Ramelteon, with IC50s of 208 pM, 1470 pM for human melatonin receptors (MT1 or MT2). Ramelteon is a selective melatonin agonist[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

278.36

Formula

C16H18D3NO3

CAS No.
SMILES

[2H]C([2H])([2H])C(O)C(NCC[[email protected]]1C2=C(CC1)C=CC3=C2CCO3)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ramelteon metabolite M-II-d3
Cat. No.:
HY-103005S
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