2. GPCR/G Protein
  3. Angiotensin Receptor
  4. Azilsartan mepixetil

Azilsartan mepixetil  (Synonyms: QR-01019)

Cat. No.: HY-145552 Purity: 98.08%
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Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A).

For research use only. We do not sell to patients.

Azilsartan mepixetil Chemical Structure

Azilsartan mepixetil Chemical Structure

CAS No. : 1596357-16-2

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Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 142 In-stock
Solution
10 mM * 1 mL in DMSO USD 142 In-stock
Solid
5 mg USD 95 In-stock
10 mg USD 165 In-stock
25 mg USD 345 In-stock
50 mg USD 550 In-stock
100 mg USD 950 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A)[1].

IC50 & Target

angiotensin II receptor[1]
Molecular Weight

678.69

Formula

C36H34N6O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC(C)OC(C1=CC=CC2=C1N(CC3=CC=C(C4=C(C5=NOC(N5)=O)C=CC=C4)C=C3)C(OCC)=N2)=O)OCC6=NC(C)=C(C)N=C6C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (294.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4734 mL 7.3671 mL 14.7343 mL
5 mM 0.2947 mL 1.4734 mL 2.9469 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4734 mL 7.3671 mL 14.7343 mL 36.8357 mL
5 mM 0.2947 mL 1.4734 mL 2.9469 mL 7.3671 mL
10 mM 0.1473 mL 0.7367 mL 1.4734 mL 3.6836 mL
15 mM 0.0982 mL 0.4911 mL 0.9823 mL 2.4557 mL
20 mM 0.0737 mL 0.3684 mL 0.7367 mL 1.8418 mL
25 mM 0.0589 mL 0.2947 mL 0.5894 mL 1.4734 mL
30 mM 0.0491 mL 0.2456 mL 0.4911 mL 1.2279 mL
40 mM 0.0368 mL 0.1842 mL 0.3684 mL 0.9209 mL
50 mM 0.0295 mL 0.1473 mL 0.2947 mL 0.7367 mL
60 mM 0.0246 mL 0.1228 mL 0.2456 mL 0.6139 mL
80 mM 0.0184 mL 0.0921 mL 0.1842 mL 0.4604 mL
100 mM 0.0147 mL 0.0737 mL 0.1473 mL 0.3684 mL
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Azilsartan mepixetil Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azilsartan mepixetil1596357-16-2QR-01019QR01019QR 01019Angiotensin Receptorangiotensin II receptorhypertensionchronic heart failurediabetic nephropathyblood pressureprotective effectheartkidneyInhibitorinhibitorinhibit

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