Topoisomerase II inhibitor 11
Topoisomerase II inhibitor 11 (compound 3d) is a potent Topoisomerase II inhibitor, with an IC50 of 2.89 μM. Topoisomerase II inhibitor 11 shows 92.46% inhibition on renal cancer cell line A498 with an IC50 of 3.5 μM. Topoisomerase II inhibitor 11 causes cell cycle arrest at the G2/M phase leading to cell proliferation inhibition and pro-apoptotic activity.
For research use only. We do not sell to patients.
- CAS No.: 2476559-00-7
- Formula: C27H21BrCl2N2O2S
- Molecular Weight:588.34
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Topoisomerase Isoforms
More
Biological Activity
Description
IC50 & Target
|
Topoisomerase II 2.89 μM (IC50) |
Chemical Information
-
CAS No. 2476559-00-7
-
Molecular Weight 588.34
-
Formula C27H21BrCl2N2O2S
-
SMILES
O=C(C1=C(C2=CC=CC=C2)N=C(SC=C3C4=CC=C(Cl)C=C4)N3C1C5=CC=C(Cl)C=C5)OCC.[H]Br
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Topoisomerase II inhibitor 11 Related Classifications
HY-147861 Related Classifications
Powered by Bioz