2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. PTP1B-IN-15

PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). PTP1B-IN-15 has the potential for the research of type II diabetes and obesity.

For research use only. We do not sell to patients.

PTP1B-IN-15 Chemical Structure

PTP1B-IN-15 Chemical Structure

CAS No. : 765317-71-3

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 308 In-stock
Solution
10 mM * 1 mL in DMSO USD 308 In-stock
Solid
5 mg USD 280 In-stock
10 mg USD 380 In-stock
25 mg USD 780 In-stock
50 mg USD 1200 In-stock
100 mg USD 1950 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

PTP1B-IN-15 Related Antibodies

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Description

PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). PTP1B-IN-15 has the potential for the research of type II diabetes and obesity[1].

IC50 & Target

PTP1B[1]
Molecular Weight

531.21

Formula

C19H17Br2NO5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCC1=C(C(C2=CC(Br)=C(O)C(Br)=C2)=O)C(C=CC(S(=O)(N(C)C)=O)=C3)=C3O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (470.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8825 mL 9.4125 mL 18.8249 mL
5 mM 0.3765 mL 1.8825 mL 3.7650 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8825 mL 9.4125 mL 18.8249 mL 47.0624 mL
5 mM 0.3765 mL 1.8825 mL 3.7650 mL 9.4125 mL
10 mM 0.1882 mL 0.9412 mL 1.8825 mL 4.7062 mL
15 mM 0.1255 mL 0.6275 mL 1.2550 mL 3.1375 mL
20 mM 0.0941 mL 0.4706 mL 0.9412 mL 2.3531 mL
25 mM 0.0753 mL 0.3765 mL 0.7530 mL 1.8825 mL
30 mM 0.0627 mL 0.3137 mL 0.6275 mL 1.5687 mL
40 mM 0.0471 mL 0.2353 mL 0.4706 mL 1.1766 mL
50 mM 0.0376 mL 0.1882 mL 0.3765 mL 0.9412 mL
60 mM 0.0314 mL 0.1569 mL 0.3137 mL 0.7844 mL
80 mM 0.0235 mL 0.1177 mL 0.2353 mL 0.5883 mL
100 mM 0.0188 mL 0.0941 mL 0.1882 mL 0.4706 mL
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PTP1B-IN-15 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PTP1B-IN-15765317-71-3Phosphataseelectivetype II diabetesobesityInhibitorinhibitorinhibit

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