[Sar1, Ile8]-Angiotensin II TFA
Based on 1 Customer Validation
[Sar1, Ile8]-Angiotensin II (TFA) is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 2918768-31-5
- Formula: C48H74F3N13O12
- Molecular Weight:1082.18
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Angiotensin Receptor Isoforms
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Biological Activity
[Sar1, Ile8]-Angiotensin II (TFA) has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. [Sar1, Ile8]-Angiotensin II (TFA) activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2918768-31-5
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Appearance Solid
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Molecular Weight 1082.18
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Formula C48H74F3N13O12
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Color White to off-white
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Sequence
{SAR}-Arg-Val-Tyr-Ile-His-Pro-Ile
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Sequence Shortening
{SAR}-RVYIHPI
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (92.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 50 mg/mL (46.20 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.9241 mL | 4.6203 mL | 9.2406 mL | 23.1015 mL |
| 5 mM | 0.1848 mL | 0.9241 mL | 1.8481 mL | 4.6203 mL | |
| 10 mM | 0.0924 mL | 0.4620 mL | 0.9241 mL | 2.3102 mL | |
| 15 mM | 0.0616 mL | 0.3080 mL | 0.6160 mL | 1.5401 mL | |
| 20 mM | 0.0462 mL | 0.2310 mL | 0.4620 mL | 1.1551 mL | |
| 25 mM | 0.0370 mL | 0.1848 mL | 0.3696 mL | 0.9241 mL | |
| 30 mM | 0.0308 mL | 0.1540 mL | 0.3080 mL | 0.7701 mL | |
| 40 mM | 0.0231 mL | 0.1155 mL | 0.2310 mL | 0.5775 mL | |
| DMSO | 50 mM | 0.0185 mL | 0.0924 mL | 0.1848 mL | 0.4620 mL |
| 60 mM | 0.0154 mL | 0.0770 mL | 0.1540 mL | 0.3850 mL | |
| 80 mM | 0.0116 mL | 0.0578 mL | 0.1155 mL | 0.2888 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.