[Sar1, Ile8]-Angiotensin II TFA  (Synonyms: AngiotensinII TFA; Angiotensin 2 TFA)

[Sar1, Ile8]-Angiotensin II (TFA) is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

[Sar1, Ile8]-Angiotensin II (TFA) has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. [Sar1, Ile8]-Angiotensin II (TFA) activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1082.18

C₄₈H₇₄F₃N₁₃O₁₂

Solid

White to off-white

{SAR}-Arg-Val-Tyr-Ile-His-Pro-Ile

{SAR}-RVYIHPI

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Griendling KK, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994 Jun;74(6):1141-8.  [Content Brief]