Cepharanone B
Based on 1 Customer Validation
Cepharanone B is a fluorescent component isolated from the callus tissue of stephania cephaiuntha.
For research use only. We do not sell to patients.
- CAS No.: 53948-09-7
- Formula: C17H13NO3
- Molecular Weight:279.29
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B-cell | IC50 |
7.11 μM
Compound: 23
|
Inhibition of LPS-induced BALB/c mouse B cell proliferation
Inhibition of LPS-induced BALB/c mouse B cell proliferation
|
[PMID: 17081761] |
| BV-2 | IC50 |
>50 μM
Compound: 26
|
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
|
[PMID: 33822610] |
| HCT-15 | GI50 |
>30 μM
Compound: 5
|
Antiproliferative activity against human HCT15 cells by SRB assay
Antiproliferative activity against human HCT15 cells by SRB assay
|
[PMID: 19394218] |
| HCT-15 | GI50 |
>30 μM
Compound: 5
|
Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay
Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay
|
[PMID: 19394218] |
| MES-SA | GI50 |
>30 μM
Compound: 5
|
Antiproliferative activity against human MESSA cells by SRB assay
Antiproliferative activity against human MESSA cells by SRB assay
|
[PMID: 19394218] |
| MES-SA/Dx5 | GI50 |
>30 μM
Compound: 5
|
Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay
Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay
|
[PMID: 19394218] |
| T-cell | IC50 |
6.96 μM
Compound: 23
|
Inhibition of ConA-induced BALB/c mouse T cell proliferation
Inhibition of ConA-induced BALB/c mouse T cell proliferation
|
[PMID: 17081761] |
Chemical Information
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CAS No. 53948-09-7
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Appearance Solid
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Molecular Weight 279.29
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Formula C17H13NO3
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Color Off-white to light yellow
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SMILES
O=C1NC2=C3C1=CC(OC)=C(OC)C3=C4C(C=CC=C4)=C2
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Synonyms
Aristolactam B II
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)