1. Natural Products
  2. Alkaloids
  3. Indole Alkaloids

Indole Alkaloids

Indole Alkaloids (203):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15141
    Staurosporine 62996-74-1 99.98%
    Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer.
  • HY-A0190
    Ceruletide 17650-98-5 99.96%
    Ceruletide is a decapeptide and a potent cholecystokinin receptor agonist. Ceruletide is a safe and effective cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts.
  • HY-18569
    3-Indoleacetic acid 87-51-4 99.97%
    3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid
  • HY-N0117
    Indirubin 479-41-4 98.74%
    Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia.
  • HY-N0737A
    Harmine 442-51-3 99.88%
    Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT2A serotonin receptor, with an Ki of 397 nM.
  • HY-N3711
    Dehydrocrenatine 26585-13-7
    Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects.
  • HY-N3461
    Isorauhimbine 483-09-0
    Isorauhimbine is an alkaloid, can be isolated from R. serpentina.
  • HY-117396
    Isomahanimbine 26871-46-5
    Isomahanimbine is a natural carbazole alkaloid found in Murraya koenigii (L.) Spreng.
  • HY-N2143
    Fumitremorgin C 118974-02-0 99.20%
    Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor.
    Fumitremorgin C
  • HY-W007376
    Indole-3-carboxaldehyde 487-89-8 99.96%
    Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin.
  • HY-N0480
    Reserpine 50-55-5 99.88%
    Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
  • HY-N2022
    Castanospermine 79831-76-8 ≥98.0%
    Castanospermine inhibits all forms of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids).
  • HY-N0170
    Indole-3-carbinol 700-06-1 ≥98.0%
    Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).
  • HY-N6732
    K-252a 99533-80-9 99.45%
    K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.
  • HY-N0480A
    Reserpine hydrochloride 16994-56-2 99.90%
    Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
    Reserpine hydrochloride
  • HY-13295
    Vinpocetine 42971-09-5 99.57%
    Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders.
  • HY-12715
    Yohimbine 146-48-5 98.10%
    Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM.
  • HY-W016784
    Indole-3-acetamide 879-37-8 99.95%
    Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class.
  • HY-40161
    Indole-3-carboxylic acid 771-50-6 99.95%
    Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases.
    Indole-3-carboxylic acid
  • HY-B1167
    Ajmaline 4360-12-7 99.82%
    Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia.