1. Peptides

Ceruletide (Synonyms: Caerulein; Cerulein)

Cat. No.: HY-A0190 Purity: 99.59%
Data Sheet SDS Handling Instructions

Ceruletide (Caerulein) is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea. It is a potent cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts in humans and

For research use only. We do not sell to patients.
Ceruletide Chemical Structure

Ceruletide Chemical Structure

CAS No. : 17650-98-5

Size Price Stock Quantity
10 mM * 1 mL in Water $893 In-stock
1 mg $90 In-stock
5 mg $330 In-stock
10 mg $600 In-stock
50 mg   Get quote  
100 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Ceruletide (Caerulein) is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea. It is a potent cholecystokinetic agent with a direct spasmogenic effect on the gallbladder muscle and bile ducts in humans and

In Vitro

Ceruletide is similar chemically and biologically to the human gastrointestinal hormones cholecystokinin-pancreozymin (CCK) and gastrin II. Ceruletide stimulates gallbladder contraction, pancreatic exocrine secretion, gastric secretion, and motility in the distal duodenum, jejunum, ileum and colon, while delaying gastric emptying and inhibiting motility in the proximal duodenum[1]. NF-kappaB/Rel is rapidly activated during cerulein pancreatitis. This activation may induce a self-defending genetic program before the onset of cellular injury, which might prevent higher degrees of damage of pancreatic acinar cells after secretagogue hyperstimulation[2].

References
Molecular Weight

1352.41

Formula

C₅₈H₇₃N₁₃O₂₁S₂

CAS No.

17650-98-5

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: ≥ 100 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Ceruletide
Cat. No.:
HY-A0190
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