392-12-1
392-12-1
Chemical Structure
Indole-3-pyruvic acid
- CAS No.: 392-12-1
- Formula:C11H9NO3
- Molecular Weight:203.19
IUPAC Name: 3-(1H-indol-3-yl)-2-oxopropanoic acid
InChIKey: RSTKLPZEZYGQPY-UHFFFAOYSA-N
SMILES: O=C(O)C(CC1=CNC2=CC=CC=C12)=O
Biological Activity: Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety[1][2][3].
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Indole-3-pyruvic acid | 99.55% | Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety. | ||||||||||||||||||||
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Indole-3-pyruvic acid (Standard) | 99.38% | Indole-3-pyruvic acid (Standard) is the analytical standard of Indole-3-pyruvic acid. This product is intended for research and analytical applications. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety. | ||||||||||||||||||||
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Indole-3-pyruvic acid-d5 | 96.31% | Indole-3-pyruvic acid-d5 is deuterated labeled Indole-3-pyruvic acid. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety. | ||||||||||||||||||||
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References
- [1]. Reiji Aoki, et al. Indole-3-Pyruvic Acid, an Aryl Hydrocarbon Receptor Activator, Suppresses Experimental Colitis in Mice. J Immunol. 2018 Dec 15;201(12):3683-3693. [Content Brief]
- [2]. Reiji Aoki, et al. Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. PLoS One. 2014 May 8;9(5):e96804. [Content Brief]
- [3]. I P Lapin, et al. Anxiolytic effect of indole-3-pyruvic acid (IPA) in mice. Pharmacol Res. 1993 Sep;28(2):129-34. [Content Brief]
