Indole-3-acetamide-d5
Based on 1 Customer Validation
Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class.
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- Pureté : 99.99%
- CAS No.: 1204700-53-7
- Formule: C10H5D5N2O
- Masse moléculaire:179.23
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1204700-53-7
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Unlabeled CAS 879-37-8
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Appearance Solid
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Masse moléculaire 179.23
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Formule C10H5D5N2O
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Color White to off-white
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SMILES
[2H]C1=C([2H])C([2H])=C([2H])C2=C1NC([2H])=C2CC(N)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 50 mg/mL (278.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Thomas Lehmann, et al. Indole-3-acetamide-dependent auxin biosynthesis: a widely distributed way of indole-3-acetic acid production? Eur J Cell Biol. 2010 Dec;89(12):895-905. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.5794 mL | 27.8971 mL | 55.7942 mL | 139.4856 mL |
| 5 mM | 1.1159 mL | 5.5794 mL | 11.1588 mL | 27.8971 mL | |
| 10 mM | 0.5579 mL | 2.7897 mL | 5.5794 mL | 13.9486 mL | |
| 15 mM | 0.3720 mL | 1.8598 mL | 3.7196 mL | 9.2990 mL | |
| 20 mM | 0.2790 mL | 1.3949 mL | 2.7897 mL | 6.9743 mL | |
| 25 mM | 0.2232 mL | 1.1159 mL | 2.2318 mL | 5.5794 mL | |
| 30 mM | 0.1860 mL | 0.9299 mL | 1.8598 mL | 4.6495 mL | |
| 40 mM | 0.1395 mL | 0.6974 mL | 1.3949 mL | 3.4871 mL | |
| 50 mM | 0.1116 mL | 0.5579 mL | 1.1159 mL | 2.7897 mL | |
| 60 mM | 0.0930 mL | 0.4650 mL | 0.9299 mL | 2.3248 mL | |
| 80 mM | 0.0697 mL | 0.3487 mL | 0.6974 mL | 1.7436 mL | |
| 100 mM | 0.0558 mL | 0.2790 mL | 0.5579 mL | 1.3949 mL |
Indole-3-acetamide-d5 Related Classifications
HY-W016784S Related Classifications
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