771-50-6
771-50-6
Chemical Structure
Indole-3-carboxylic acid
- CAS No.: 771-50-6
- Formula:C9H7NO2
- Molecular Weight:161.16
IUPAC Name: 1H-indole-3-carboxylic acid
InChIKey: KMAKOBLIOCQGJP-UHFFFAOYSA-N
SMILES: O=C(O)C1=CNC2=CC=CC=C12
Biological Activity: Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease research[1][2][3][4].
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Indole-3-carboxylic acid | 99.96% | Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease research. | ||||||||||||||||||||
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Indole-3-carboxylic acid (Standard) | 99.58% | Indole-3-carboxylic acid (Standard) is the analytical standard of Indole-3-carboxylic acid. This product is intended for research and analytical applications. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases. | ||||||||||||||||||||
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Indole-3-carboxylic acid-d4 | Indole-3-carboxylic acid-d4 is deuterium labeled Indole-3-carboxylic acid. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases. | |||||||||||||||||||||
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References
- [1]. Byrd DJ, et al. The analysis of indolic tryptophan metabolites in human urine. Thin-layer chromatography and in situ quantitation. J Chromatogr. 1974 Jul 17;94(0):85-106. [Content Brief]
- [2]. HARTMANN F, et al. [Indolepatterns in the urine of liver patients]. Klin Wochenschr. 1962 Jul 15;40:721-9. [Content Brief]
- [3]. Gamir J, et al. Identification of indole-3-carboxylic acid as mediator of priming against Plectosphaerella cucumerina. Plant Physiol Biochem. 2012 Dec;61:169-79. [Content Brief]
- [4]. ZHOU Y A O, et al. INDOLE-3-CARBOXYLIC ACID ENHANCED ANTI-CANCER POTENCY OF DOXORUBICIN VIA INDUCTION OF CELLULAR SENESCENCE IN COLORECTAL CELLS. Acta Poloniae Pharmaceutica, 2024, 81(1).
