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Cat. No.: HY-W015420

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1H-Indole-6-carboxylic acid

Name: 1H-Indole-6-carboxylic acid
Brand: MedChemExpress
SKU: HY-W015420
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

1 Cited Publications

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1H-Indole-6-carboxylic acid is an allosteric binder of HIV-1 protease. 1H-Indole-6-carboxylic acid can be used in studies related to HIV-1 infection.

For research use only. We do not sell to patients.

Purity: 99.23%
CAS No.: 1670-82-2
Formula: C₉H₇NO₂
Molecular Weight:161.16

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

1H-Indole-6-carboxylic acid Chemical Structure

CAS No.: 1670-82-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
Publications (1)
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Biological Activity

Description

1H-Indole-6-carboxylic acid is an allosteric binder of HIV-1 protease. 1H-Indole-6-carboxylic acid can be used in studies related to HIV-1 infection^[1].

In Vitro

Binding of 1H-Indole-6-carboxylic acid to the top site of HIV-1 protease chain B stabilizes the protease and the 3TL-protease complex, inhibits the flexibility of the enzyme flaps, increases the binding affinity between 3TL and the protease by approximately 12-15 kcal/mol, and simultaneously causes partial opening of the protease flaps^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1670-82-2
Appearance Solid
Molecular Weight 161.16
Formula C₉H₇NO₂
Color White to off-white
SMILES

O=C(C1=CC2=C(C=C1)C=CN2)O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Publications (1)

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2026 Apr 23.

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Meng XM, et al. Effect of allosteric molecules on structure and drug affinity of HIV-1 protease by molecular dynamics simulations. Journal of molecular graphics & modelling. 2016 Nov;70:153-162. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

1H-Indole-6-carboxylic acid

1 Cited Publications

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Biological Activity
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Publications (1)
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1H-Indole-6-carboxylic acid

5-Methoxyindole-3-acetic acid

Methyl indole-3-carboxylate

Ethyl indole-2-carboxylate

2,3-Dimethylindole

5-Methoxyindole-3-acetic acid (Standard)

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Publications Citing Use of MedChemExpress (MCE) 1H-Indole-6-carboxylic acid

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

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Help & FAQs

Bioz

1H-Indole-6-carboxylic acid

5-Methoxyindole-3-acetic acid

Methyl indole-3-carboxylate

Ethyl indole-2-carboxylate

2,3-Dimethylindole

5-Methoxyindole-3-acetic acid (Standard)

Methyl indole-3-carboxylate (Standard)

Publications Citing Use of MedChemExpress (MCE) 1H-Indole-6-carboxylic acid

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

1H-Indole-6-carboxylic acid Related Classifications

HY-W015420 Related Classifications

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