479-41-4
479-41-4
Chemical Structure
Indirubin
Synonym(s): Couroupitine B; Indigo red; Indigopurpurin
- CAS No.: 479-41-4
- Formula:C16H10N2O2
- Molecular Weight:262.26
IUPAC Name: (E)-[2,3'-biindolinylidene]-2',3-dione
InChIKey: CRDNMYFJWFXOCH-BUHFOSPRSA-N
SMILES: O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C\3=O
Biological Activity: Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia[1][2].
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Indirubin | 99.37% | Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia. | ||||||||||||||||||||
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Indirubin (Standard) | 97.45% | Indirubin (Standard) is the analytical standard of Indirubin. This product is intended for research and analytical applications. Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-N0117AR(Z)-Indirubin (Standard) -
Similarity Score 0.76
HY-139254Indirubin-3′-oxime -
Similarity Score 0.76
HY-19807Indirubin-3'-monoxime -
Similarity Score 0.73
HY-111932Indirubin-5-sulfonate -
Similarity Score 0.72
HY-N0335Indigo -
Similarity Score 0.72
HY-107869Isoindigo -
Similarity Score 0.64
HY-13680Meisoindigo -
Similarity Score 0.64
HY-18785Indirubin Derivative E804 -
Similarity Score 0.64
HY-1119305-Iodo-indirubin-3'-monoxime -
Explore the MedChemAI to find more analogs
References
- [1]. Kim MH, et al. Indirubin, a purple 3,2- bisindole, inhibited allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model. J Ethnopharmacol. 2013 Jan 9;145(1):214-9. [Content Brief]
- [2]. Hsieh WL, et al. Indirubin, an acting component of indigo naturalis, inhibits EGFR activation and EGF-induced CDC25B gene expression in epidermal keratinocytes. J Dermatol Sci. 2012 Aug;67(2):140-6. [Content Brief]
