1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. Cyclopiazonic acid

Cyclopiazonic acid 

Cat. No.: HY-N6771 Purity: ≥98.0%
Handling Instructions

Cyclopiazonic acid (CPA), a neurotoxic secondary metabolite (SM) made by A. flavus, is a nanomolar inhibitor of endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA) and a potent inducer of cell death in plants.

For research use only. We do not sell to patients.

Cyclopiazonic acid Chemical Structure

Cyclopiazonic acid Chemical Structure

CAS No. : 18172-33-3

Size Price Stock Quantity
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 430 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

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Description

Cyclopiazonic acid (CPA), a neurotoxic secondary metabolite (SM) made by A. flavus, is a nanomolar inhibitor of endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA) and a potent inducer of cell death in plants[1].

Molecular Weight

336.38

Formula

C₂₀H₂₀N₂O₃

CAS No.
SMILES

O=C1C(C(C)=O)=C(O)[[email protected]@]([[email protected]]23[H])([H])N1C(C)(C)[[email protected]]2([H])CC4=CC=CC5=C4C3=CN5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (297.28 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9728 mL 14.8641 mL 29.7283 mL
5 mM 0.5946 mL 2.9728 mL 5.9457 mL
10 mM 0.2973 mL 1.4864 mL 2.9728 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.43 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.43 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: ≥99.0%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cyclopiazonic acidCalcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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Product Name:
Cyclopiazonic acid
Cat. No.:
HY-N6771
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