1. Natural Products
  2. Alkaloids
  3. Pyrrole Alkaloids

Pyrrole Alkaloids

Pyrrole Alkaloids (139):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14944
    Homoharringtonine 26833-87-4 99.96%
    Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.
  • HY-N0862
    Harringtonine 26833-85-2 99.93%
    Harringtonine is a natural Cephalotaxus alkaloid that inhibits protein synthesis. Harringtonine has anti-chikungunya virus (CHIKV) activities with an EC50 of 0.24 μM.
  • HY-16050
    Plitidepsin 137219-37-5 99.88%
    Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( KD=80 nM). Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC90 of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research.
  • HY-N0750
    Monocrotaline 315-22-0 98.08%
    Monocrotaline is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria pallida plant to induce pulmonary hypertension in rodents.
  • HY-N0288
    Lycorine 476-28-8 98.89%
    Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases.
  • HY-N11677
    7-Hydroxy-TSU-68 1035154-52-9
    7-Hydroxy-TSU-68 is a derivative of TSU-68 (HY-10517). It is a metabolite of the biotransformation pathway of TSU-68 in human liver microsomes. The content represents the self-induced hydroxylation level of TSU-68.
  • HY-N11562
    Aristololactam II 55610-00-9
    Aristololactam II, a metabolite of Aristolochic acid II (AAII), is an excretion product found in the urine, which is considered to be detoxification metabolite of AAII.
    Aristololactam II
  • HY-N1208
    Spiradine F 21040-64-2
    Spiradine F is a main alkaloidal component of spiraea japonioa L. fil. Spiradine F derivative can inhibit platelet-activating factor (PAF)-induced platelet aggregation.
    Spiradine F
  • HY-N6638
    Retrorsine 480-54-6 99.63%
    Retrorsine is a naturally occurring toxic pyrrolizidine alkaloid. Retrorsine can bind with DNA and inhibits the proliferative capacity of hepatocytes. Retrorsine can be used for the research of hepatocellular injury.
  • HY-N0289
    Lycorine hydrochloride 2188-68-3 99.89%
    Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (L’Her.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity. Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells (IC50 of 1.2 μM).
    Lycorine hydrochloride
  • HY-N2309
    Kainic acid 487-79-6 99.84%
    Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.
    Kainic acid
  • HY-40135
    L-Hydroxyproline,BioReagent, suitable for cell culture 51-35-4 ≥98.0%
    L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
    L-Hydroxyproline,BioReagent, suitable for cell culture
  • HY-N0638
    Dendrobine 2115-91-5 ≥98.0%
    Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses, with IC50s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively.
  • HY-N0095
    (S)-10-Hydroxycamptothecin 19685-09-7 99.38%
    (S)-10-Hydroxycamptothecin (10-HCPT;10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor of isolated from the Chinese plant Camptotheca accuminata. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis-inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia treatment.
  • HY-N0738
    Stachydrine hydrochloride 4136-37-2 ≥98.0%
    Stachydrine hydrochloride is the major active constituent of Leonurus artemisia, which is a potential therapy for cardiovascular diseases. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities.
    Stachydrine hydrochloride
  • HY-P1902A
    Cardiotoxin Analog (CTX) IV (6-12) (TFA) 99.88%
    Cardiotoxin Analog (CTX) IV (6-12) (TFA) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. CTX IV is an unique snake venom cardiotoxin.
    Cardiotoxin Analog (CTX) IV (6-12) (TFA)
  • HY-N0298
    Stachydrine 471-87-4 ≥98.0%
    Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.
  • HY-N6771
    Cyclopiazonic acid 18172-33-3 ≥99.0%
    Cyclopiazonic acid (CPA), a neurotoxic secondary metabolite (SM) made by Aspergillus flavus, is an inhibitor of endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA) and a potent inducer of cell death in plants.
    Cyclopiazonic acid
  • HY-111914A
    Ferroheme 14875-96-8
    Ferroheme, a complex of ferrous iron and a porphyrin, is an isosteric inhibitor of fatty acid binding to rat liver fatty acid binding protein.
  • HY-129071
    Vindesine sulfate 59917-39-4 99.40%
    Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo.
    Vindesine sulfate