2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. L-Hydroxyproline

L-Hydroxyproline  (Synonyms: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid)

Cat. No.: HY-40135 Purity: 99.89%
COA
SDS
Handling Instructions Technical Support

L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

L-Hydroxyproline

L-Hydroxyproline 화학구조

CAS No. : 51-35-4

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in Water 해외재고보유
Solid
500 mg 해외재고보유
5 g 해외재고보유
10 g 해외재고보유
25 g 해외재고보유
50 g 해외재고보유
100 g 해외재고보유
500 g 해외재고보유
> 100 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 2 publication(s) in Google Scholar

Other Forms of L-Hydroxyproline:

L-Hydroxyproline Related Antibodies

Top Publications Citing Use of Products

View All Endogenous Metabolite Isoform Specific Products:

View All Isoforms
Human Endogenous Metabolite Microbial Metabolite

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

L-Hydroxyproline (Trans-4-hydroxy-L-proline;Trans-Hyp) has been widely used in medicine, biochemistry, food, cosmetic and other aspects of industry. Additionally, L-Hydroxyproline has also been found in the composition of some secondary metabolites such as actinomycins and echinocandins. L-Hydroxyproline is manufactured industrially most by acid hydrolysis of mammalian collagen because of its rich amount in the collagen[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Hydroxyproline Related Antibodies
분자량

131.13

화학식

C5H9NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@H](C1)NC[C@@H]1O
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
용액&용해도
In Vitro: 

H2O : 50 mg/mL (381.30 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6260 mL 38.1301 mL 76.2602 mL
5 mM 1.5252 mL 7.6260 mL 15.2520 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (762.60 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.89%

SDS (393 KB)

COA (251 KB) RP-HPLC (207 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.6260 mL 38.1301 mL 76.2602 mL 190.6505 mL
5 mM 1.5252 mL 7.6260 mL 15.2520 mL 38.1301 mL
10 mM 0.7626 mL 3.8130 mL 7.6260 mL 19.0650 mL
15 mM 0.5084 mL 2.5420 mL 5.0840 mL 12.7100 mL
20 mM 0.3813 mL 1.9065 mL 3.8130 mL 9.5325 mL
25 mM 0.3050 mL 1.5252 mL 3.0504 mL 7.6260 mL
30 mM 0.2542 mL 1.2710 mL 2.5420 mL 6.3550 mL
40 mM 0.1907 mL 0.9533 mL 1.9065 mL 4.7663 mL
50 mM 0.1525 mL 0.7626 mL 1.5252 mL 3.8130 mL
60 mM 0.1271 mL 0.6355 mL 1.2710 mL 3.1775 mL
80 mM 0.0953 mL 0.4766 mL 0.9533 mL 2.3831 mL
100 mM 0.0763 mL 0.3813 mL 0.7626 mL 1.9065 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Hydroxyproline Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Hydroxyproline51-35-4(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acidEndogenous MetaboliteInhibitorinhibitorinhibit

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상품명:
L-Hydroxyproline
Cat. No.:
HY-40135
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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