51-35-4
51-35-4
Chemical Structure
L-Hydroxyproline
Synonym(s): (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid
- CAS No.: 51-35-4
- Formula:C5H9NO3
- Molecular Weight:131.13
IUPAC Name: (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
InChIKey: PMMYEEVYMWASQN-DMTCNVIQSA-N
SMILES: O=C(O)[C@H](C1)NC[C@@H]1O
Biological Activity: L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
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L-Hydroxyproline | 99.89% | L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. | ||||||||||||||||||||
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L-Hydroxyproline (Standard) | 99.89% | L-Hydroxyproline (Standard) is the analytical standard of L-Hydroxyproline. This product is intended for research and analytical applications. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. | ||||||||||||||||||||
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L-Hydroxyproline-d3 | 99.94% | L-Hydroxyproline-d3 is the deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. | ||||||||||||||||||||
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L-Hydroxyproline-d4 | 99.85% | L-Hydroxyproline-d4 is deuterium labeled L-Hydroxyproline. L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals. | ||||||||||||||||||||
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L-Prolinamide-d3 | L-Prolinamide-d3 is the deuterium labeled L-Prolinamide. L-Prolinamide is a proline derivative. | |||||||||||||||||||||
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(4S)-4-Hydroxy-D-proline | 99.95% | (4S)-4-Hydroxy-D-proline is a D-proline derivative and aglycon core for synthesis of cell wall O-glycans of the green alga Chlamydomonas reinhardtii. | ||||||||||||||||||||
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cis-4-Hydroxy-L-proline (Standard) | 98.2% | cis-4-Hydroxy-L-proline (Standard) is the analytical standard of cis-4-Hydroxy-L-proline (HY-40136). This product is intended for research and analytical applications. cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension. | ||||||||||||||||||||
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(R)-Pyrrolidine-2-carboxylic acid-d3 | (R)-Pyrrolidine-2-carboxylic acid-d3 is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite. | |||||||||||||||||||||
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L-Pyroglutamic acid-d5 | 98.6% | L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. | ||||||||||||||||||||
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(2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride | 99.89% | cis-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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cis-3-Hydroxyproline | 95.0% | cis-L-3-Hydroxyproline is an Alanine-Serine-Cysteine transporter 2 (ASCT2, SLC1A5) substrate that can induces inwardly-directed anion current, and forms key interactions with ASCT2 binding site residues including Asn471.cis-L-3-Hydroxyproline can be used for the research of melanoma. | ||||||||||||||||||||
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tans-4-Hydroxy-D-proline hydrochloride | 97.0% | tans-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR | ||||||||||||||||||||
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H-D-cis-Hyp-OH (Standard) | ≥98% | H-D-cis-Hyp-OH (Standard) is the analytical standard of H-D-cis-Hyp-OH. This product is used for research and analytical applications. H-D-cis-Hyp-OH is a proline derivative and also a substrate of the cis-4-hydroxy-D-proline dehydrogenase from the alfalfa rhizobium (Sinorhizobium meliloti). H-D-cis-Hyp-OH can be used as an initial raw material for the synthesis of conformationally restricted pyrrolidine PNA adenine monomers. | ||||||||||||||||||||
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DL-Pyroglutamic acid-d5 | 99.21% | DL-Pyroglutamic acid-d5 is the deuterium labeled DL-Pyroglutamic acid. | ||||||||||||||||||||
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DL-Proline-d7 | 98.0% | DL-Proline-d7 is the deuterated-labeled DL-Proline (HY-W012908). DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections. | ||||||||||||||||||||
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DL-Proline-2-d1 | 98.0% | DL-Proline-2-d1 is the deuterated-labeled DL-Proline (HY-W012908). DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections. | ||||||||||||||||||||
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DL-Proline-d3 | 99.67% | DL-Proline-d3 is the deuterated-labeled DL-Proline (HY-W012908). DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections. | ||||||||||||||||||||
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cis-4-Hydroxy-L-proline hydrochloride | 97.0% | cis-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-L-proline hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Pyrrolidin-3-ol-d5 | 98.1% | Pyrrolidin-3-ol-d5 is the deuterium labeled Pyrrolidin-3-ol. | ||||||||||||||||||||
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(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid | 98.0% | (2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid is a proline derivative. | ||||||||||||||||||||
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Hydroxyproline | 98.0% | Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagenous tissues. Hydroxyproline acts as a substrate for mitochondrial hydroxyproline oxidase to generate ROS. Hydroxyproline promotes the synthesis of glutathione, DNA, heme and proteins via conversion to Glycine (HY-Y0966). Hydroxyproline promotes the activation of caspase-9 and apoptosis in cancer cells treated with Doxorubicin. Hydroxyproline serves as a biochemical marker. Hydroxyproline is used in research related to various diseases including colon cancer, diabetes and arthritis. | ||||||||||||||||||||
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3-Hydroxyproline | 3-Hydroxyproline is a non-glycosyl microbial α-glucosidase inhibitor. 3-Hydroxyproline is used in the research of diabetes (type 2 diabetes/non-insulin-dependent diabetes mellitus). | |||||||||||||||||||||
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L-Proline-d3 | 99.84% | L-Proline-d3 is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. | ||||||||||||||||||||
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L-Proline-d7 | 99.93% | L-Proline-d7 is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. | ||||||||||||||||||||
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