1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Vindesine sulfate

Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo.

For research use only. We do not sell to patients.

Vindesine sulfate Chemical Structure

Vindesine sulfate Chemical Structure

CAS No. : 59917-39-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 150 In-stock
Solution
10 mM * 1 mL in DMSO USD 150 In-stock
Solid
5 mg USD 100 In-stock
10 mg USD 160 In-stock
25 mg USD 320 In-stock
50 mg USD 510 In-stock
100 mg USD 810 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Vindesine sulfate:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Vindesine sulfate is a potent tubulin inhibitor with an Ki of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo[1].

In Vitro

Vindesine sulfate inhibits L-cells growth and shows about 25% inhibition at 40 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

852.00

Formula

C43H57N5O11S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(O)(O)=O.CC[C@@]12[C@@]3([H])[C@@]4(CCN3CC=C2)C5=CC([C@@]6(C7=C(CC[N@]8C[C@@](C[C@](O)(C8)CC)([H])C6)C9=CC=CC=C9N7)C(OC)=O)=C(OC)C=C5N([C@@]4([H])[C@](O)([C@@H]1O)C(N)=O)C

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (293.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1737 mL 5.8685 mL 11.7371 mL
5 mM 0.2347 mL 1.1737 mL 2.3474 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.91%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1737 mL 5.8685 mL 11.7371 mL 29.3427 mL
5 mM 0.2347 mL 1.1737 mL 2.3474 mL 5.8685 mL
10 mM 0.1174 mL 0.5869 mL 1.1737 mL 2.9343 mL
15 mM 0.0782 mL 0.3912 mL 0.7825 mL 1.9562 mL
20 mM 0.0587 mL 0.2934 mL 0.5869 mL 1.4671 mL
25 mM 0.0469 mL 0.2347 mL 0.4695 mL 1.1737 mL
30 mM 0.0391 mL 0.1956 mL 0.3912 mL 0.9781 mL
40 mM 0.0293 mL 0.1467 mL 0.2934 mL 0.7336 mL
50 mM 0.0235 mL 0.1174 mL 0.2347 mL 0.5869 mL
60 mM 0.0196 mL 0.0978 mL 0.1956 mL 0.4890 mL
80 mM 0.0147 mL 0.0734 mL 0.1467 mL 0.3668 mL
100 mM 0.0117 mL 0.0587 mL 0.1174 mL 0.2934 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Vindesine sulfate
Cat. No.:
HY-129071
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