Vindesine sulfate

Name: Vindesine sulfate
Brand: MedChemExpress
SKU: HY-129071
Rating: 4.5 (1 reviews)

Cat. No.: HY-129071 Purity: 98.03%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Vindesine sulfate is a potent tubulin inhibitor with an K_i of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo.

For research use only. We do not sell to patients.

Vindesine sulfate Chemical Structure

CAS No. : 59917-39-4

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 150	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 150	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 510	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 810	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Vindesine sulfate:

Vindesine Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Vindesine sulfate is a potent tubulin inhibitor with an K_i of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo^[1].

In Vitro

Vindesine sulfate inhibits L-cells growth and shows about 25% inhibition at 40 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

852.00

Formula

C₄₃H₅₇N₅O₁₁S

CAS No.

59917-39-4

Appearance

Solid

Color

White to off-white

SMILES

O=S(O)(O)=O.CC[C@@]12[C@@]3([H])[C@@]4(CCN3CC=C2)C5=CC([C@@]6(C7=C(CC[N@]8C[C@@](C[C@](O)(C8)CC)([H])C6)C9=CC=CC=C9N7)C(OC)=O)=C(OC)C=C5N([C@@]4([H])[C@](O)([C@@H]1O)C(N)=O)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (293.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1737 mL	5.8685 mL	11.7371 mL
5 mM	0.2347 mL	1.1737 mL	2.3474 mL
10 mM	0.1174 mL	0.5869 mL	1.1737 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.40%

Select Batch:

Data Sheet (280 KB) SDS (252 KB)

COA (263 KB)

Handling Instructions (2659 KB)

References

[1]. Jordan MA, et al. Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 1985 Jun;45(6):2741-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1737 mL	5.8685 mL	11.7371 mL	29.3427 mL
	5 mM	0.2347 mL	1.1737 mL	2.3474 mL	5.8685 mL
	10 mM	0.1174 mL	0.5869 mL	1.1737 mL	2.9343 mL
	15 mM	0.0782 mL	0.3912 mL	0.7825 mL	1.9562 mL
	20 mM	0.0587 mL	0.2934 mL	0.5869 mL	1.4671 mL
	25 mM	0.0469 mL	0.2347 mL	0.4695 mL	1.1737 mL
	30 mM	0.0391 mL	0.1956 mL	0.3912 mL	0.9781 mL
	40 mM	0.0293 mL	0.1467 mL	0.2934 mL	0.7336 mL
	50 mM	0.0235 mL	0.1174 mL	0.2347 mL	0.5869 mL
	60 mM	0.0196 mL	0.0978 mL	0.1956 mL	0.4890 mL
	80 mM	0.0147 mL	0.0734 mL	0.1467 mL	0.3668 mL
	100 mM	0.0117 mL	0.0587 mL	0.1174 mL	0.2934 mL