Catharanthus roseus (L.) G. Don
Synonyms: Madagascar periwinkle

Catharanthus roseus (L.) G. Don (17):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

Vincristine sulfate	2068-78-2	99.81%
Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K_i of 85 nM.

Vinblastine sulfate	143-67-9	99.04%
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC₅₀ of 8.9 μM.

HY-12053A

Vinorelbine ditartrate 125317-39-7 99.15%

Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC₅₀ of 1.25 nM.

Vinorelbine ditartrate	125317-39-7	99.15%
Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC₅₀ of 1.25 nM.

Vinpocetine	42971-09-5	99.57%
Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na⁺ channels. The IC₅₀ value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders.

Vindesine sulfate	59917-39-4	99.40%
Vindesine sulfate is a potent tubulin inhibitor with an K_i of 0.110 µM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo.

Catharanthine	2468-21-5	99.53%
Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca²⁺ channel (VOCC). Catharanthine has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity.

trans-Zeatinriboside	6025-53-2	99.65%
trans-Zeatinriboside is a type of cytokinin precursor, acts as a major long-distance signalling form in xylem vessels, regulates leaf size and meristem activity-related traits.

Vincamine	1617-90-9	99.65%
Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research.

HY-N0687

Vindoline 2182-14-1 99.50%

Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly.

Vindoline	2182-14-1	99.50%
Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly.

Catharanthine Tartrate	4168-17-6	99.92%
Catharanthine ((+)-3,4-Didehydrocoronaridine) Tartrate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca²⁺ channel (VOCC). Catharanthine Tartrate has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Tartrate lowers blood pressure (BP), heart rate (HR). Catharanthine Tartrate has anti-cancer activity.

Catharanthine Sulfate	153230-94-5
Catharanthine ((+)-3,4-Didehydrocoronaridine) Sulfate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca²⁺ channel (VOCC). Catharanthine Sulfate has IC₅₀s of 220 μM and 8 μM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Sulfate lowers blood pressure (BP), heart rate (HR). Catharanthine Sulfate has anti-cancer activity.

HY-N1163

Tetrahydroalstonine 6474-90-4 99.95%

Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist.
HY-120098

Vinleurosine 23360-92-1

Vinleurosine is an indole alkaloid with antineoplastic activity.
HY-N0675

Anhydrovinblastine 38390-45-3

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves.
HY-N10057

5-epi-Jinkoheremol 2567930-96-3

5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.

Tetrahydroalstonine	6474-90-4	99.95%
Tetrahydroalstonine, a indole alkaloid isolated from the fruits of Rhazya stricta, is a selective alpha 2-adrenoceptor antagonist.

Vinleurosine	23360-92-1
Vinleurosine is an indole alkaloid with antineoplastic activity.

Anhydrovinblastine	38390-45-3
Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves.

5-epi-Jinkoheremol	2567930-96-3
5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.

Tabersonine hydrochloride	29479-00-3
Tabersonine hydrochloride is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and is a potential therapeutic candidate for the treatment of ALI/ARDS.

HY-N5122

Vindolinine 5980-02-9

Vindolinine is a natural alkaloide that can be found in Catharanthus roseus.

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