1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. Vincristine

Vincristine (Synonyms: Leurocristine; 22-Oxovincaleukoblastine)

Cat. No.: HY-N0488A
Handling Instructions

Vincristine (Leurocristine) is a microtubule-destabilizing agent (MDA). Vincristine (Leurocristine) binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine (Leurocristine) is used to treat hematologic cancers, such as leukemia and lymphoma, and childhood sarcomas.

For research use only. We do not sell to patients.

Vincristine Chemical Structure

Vincristine Chemical Structure

CAS No. : 57-22-7

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Top Publications Citing Use of Products

    Vincristine purchased from MCE. Usage Cited in: Int J Biol Macromol. 2019 Jan 30;128:574-582.

    SGC7901/DDP or SGC7901/VCR cells are transfectedwith si-Con or si-ERK, and transfection efficiency is evaluated by western blot assay at 48 h post transfection.
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    Description

    Vincristine (Leurocristine) is a microtubule-destabilizing agent (MDA). Vincristine (Leurocristine) binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine (Leurocristine) is used to treat hematologic cancers, such as leukemia and lymphoma, and childhood sarcomas[1][2].

    Molecular Weight

    824.96

    Formula

    C₄₆H₅₆N₄O₁₀

    CAS No.

    57-22-7

    SMILES

    CC[[email protected]@]1(C=CCN2CC3)[[email protected]@]2([H])[[email protected]@]3(C4=CC([[email protected]](C5=C6C7=CC=CC=C7N5)(C[[email protected]](C[[email protected]](CC)(O)C8)([H])C[[email protected]@]8CC6)C(OC)=O)=C(OC)C=C4N9C=O)[[email protected]]9([H])[[email protected]](C(OC)=O)(O)[[email protected]@H]1OC(C)=O

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    Please store the product under the recommended conditions in the Certificate of Analysis.

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