Alkaloid Dimers

Alkaloid Dimers (18):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

Vincristine sulfate	2068-78-2	99.81%
Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K_i of 85 nM.

Vinblastine sulfate	143-67-9	99.04%
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC₅₀ of 8.9 μM.

HY-12053A

Vinorelbine ditartrate 125317-39-7 99.15%

Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC₅₀ of 1.25 nM.

Vinorelbine ditartrate	125317-39-7	99.15%
Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC₅₀ of 1.25 nM.

Chaetocin	28097-03-2	99.46%
Chaetocin is a specific inhibitor of the histone methyltransferase (HMT) SU(VAR)3-9 with an IC₅₀ of 0.6 μM for SU(VAR)3-9. It also inhibits thioredoxin reductase (TrxR) with an IC₅₀ of 4 μM.

HY-13764

Tetrandrine 518-34-3 99.91%

Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca²⁺ current (ICa) and Ca²⁺-activated K⁺ current.

Tetrandrine	518-34-3	99.91%
Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca²⁺ current (ICa) and Ca²⁺-activated K⁺ current.

Thalidezine	18251-36-0
Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention .

Liensinine	2586-96-1	99.97%
Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.

HY-N0441

Neferine 2292-16-2 99.92%

Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation.
HY-15758

3,3'-Diindolylmethane 1968-05-4 99.93%

3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.
HY-N6045

Isotetrandrine 477-57-6

Isotetrandrine is a bioactive component in Stephania tetrandra.

Neferine	2292-16-2	99.92%
Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation.

3,3'-Diindolylmethane	1968-05-4	99.93%
3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.

Isotetrandrine	477-57-6
Isotetrandrine is a bioactive component in Stephania tetrandra.

Calycanthine	595-05-1	99.93%
Calycanthine, the principal alkaloid of the order Calycanthaceae, has been isolated from a species of the genus Psychotria, and is a central nervous system toxin, causing convulsions.

Stephacidin B	360765-75-9
Stephacidin B is a fungal metabolite. Stephacidin B shows in vitro cytotoxicity against a panel of human tumor cell lines. Stephacidin B shows the strongest cytotoxicity against testosterone-dependent prostate LNCaP cancer cells.

HY-N5118

Chimonanthine 5545-89-1

Chimonanthine is an alkaloid of Chimonanthus praecox, inhibits tyrosinase and tyrosine-related protein-1 mRNA expression, amd inhibits melanogenesis.

Chimonanthine	5545-89-1
Chimonanthine is an alkaloid of Chimonanthus praecox, inhibits tyrosinase and tyrosine-related protein-1 mRNA expression, amd inhibits melanogenesis.

Thalrugosaminine	22226-73-9
Thalrugosaminine is a benzylisoquinoline alkaloid isolated from the roots of Thalictrum minus. Thalrugosaminine shows good antibacterial activity with MIC values of 64-128 µg/ml.

HY-N8089

Bis(dihydrochelerythrinyl)amine 165393-48-6

Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity.
HY-N9338

Guattegaumerine 21446-35-5

Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.

Bis(dihydrochelerythrinyl)amine	165393-48-6
Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity.

Guattegaumerine	21446-35-5
Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.

Daurinoline	2831-75-6
Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research.

HY-N11494

Dauricumine 345641-00-1

Dauricumine is a chlorinated alkaloid that inhibits NF-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts.

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