1. Natural Products
  2. Alkaloids
  3. Alkaloid Dimers

Alkaloid Dimers

Alkaloid Dimers (18):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0488
    Vincristine sulfate 2068-78-2 99.81%
    Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
    Vincristine sulfate
  • HY-12053A
    Vinorelbine ditartrate 125317-39-7 99.15%
    Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
    Vinorelbine ditartrate
  • HY-13780
    Vinblastine sulfate 143-67-9 99.04%
    Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.
    Vinblastine sulfate
  • HY-N2019
    Chaetocin 28097-03-2 99.95%
    Chaetocin is a specific inhibitor of the histone methyltransferase (HMT) SU(VAR)3-9 with an IC50 of 0.6 μM for SU(VAR)3-9. It also inhibits thioredoxin reductase (TrxR) with an IC50 of 4 μM.
  • HY-13764
    Tetrandrine 518-34-3 99.91%
    Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
  • HY-N11494
    Dauricumine 345641-00-1
    Dauricumine is a chlorinated alkaloid that inhibits NF-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts.
  • HY-N0484
    Liensinine 2586-96-1 99.97%
    Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.
  • HY-N0441
    Neferine 2292-16-2 99.92%
    Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation.
  • HY-15758
    3,3'-Diindolylmethane 1968-05-4 99.57%
    3,3'-Diindolylmethane is a strong, pure androgen receptor (AR) antagonist.
  • HY-N6045
    Isotetrandrine 477-57-6
    Isotetrandrine is a bioactive component in Stephania tetrandra.
  • HY-N2005
    Cycleanine 518-94-5 99.80%
    Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway.
  • HY-N5121
    Calycanthine 595-05-1 99.93%
    Calycanthine, the principal alkaloid of the order Calycanthaceae, has been isolated from a species of the genus Psychotria, and is a central nervous system toxin, causing convulsions.
  • HY-N10265
    Stephacidin B 360765-75-9
    Stephacidin B is a fungal metabolite. Stephacidin B shows in vitro cytotoxicity against a panel of human tumor cell lines. Stephacidin B shows the strongest cytotoxicity against testosterone-dependent prostate LNCaP cancer cells.
    Stephacidin B
  • HY-N5118
    Chimonanthine 5545-89-1
    Chimonanthine is an alkaloid of Chimonanthus praecox, inhibits tyrosinase and tyrosine-related protein-1 mRNA expression, amd inhibits melanogenesis.
  • HY-N6078
    Thalrugosaminine 22226-73-9
    Thalrugosaminine is a benzylisoquinoline alkaloid isolated from the roots of Thalictrum minus. Thalrugosaminine shows good antibacterial activity with MIC values of 64-128 µg/ml.
  • HY-N8089
    Bis(dihydrochelerythrinyl)amine 165393-48-6
    Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity.
  • HY-N9338
    Guattegaumerine 21446-35-5
    Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.
  • HY-N2104
    Daurinoline 2831-75-6
    Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research.