1. Autophagy
  2. Autophagy
    Mitophagy
  3. Liensinine

Liensinine 

Cat. No.: HY-N0484 Purity: 99.89%
Handling Instructions

Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.

For research use only. We do not sell to patients.

Liensinine Chemical Structure

Liensinine Chemical Structure

CAS No. : 2586-96-1

Size Price Stock Quantity
5 mg USD 99 In-stock
Estimated Time of Arrival: December 31
10 mg USD 168 In-stock
Estimated Time of Arrival: December 31
20 mg USD 286 Get quote
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].

Molecular Weight

610.74

Formula

C₃₇H₄₂N₂O₆

CAS No.

2586-96-1

SMILES

OC1=CC=C(C[[email protected]]2N(C)CCC3=C2C=C(OC)C(OC)=C3)C=C1OC4=CC5=C(C=C4OC)CCN(C)[[email protected]@H]5CC6=CC=C(O)C=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (163.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6374 mL 8.1868 mL 16.3736 mL
5 mM 0.3275 mL 1.6374 mL 3.2747 mL
10 mM 0.1637 mL 0.8187 mL 1.6374 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.41 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.41 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.41 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.89%

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The molarity calculator equation

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

LiensinineAutophagyMitophagyMitochondrial AutophagyapoptosisautophagyautophagicstressbreastcancerDNM1LlysosomemitochondrialfissionRAB7AInhibitorinhibitorinhibit

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Liensinine
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