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  3. Liensinine Diperchlorate

Liensinine Diperchlorate 

Cat. No.: HY-N0485 Purity: 99.97%
Handling Instructions

Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.

For research use only. We do not sell to patients.

Liensinine Diperchlorate Chemical Structure

Liensinine Diperchlorate Chemical Structure

CAS No. : 5088-90-4

Size Price Stock Quantity
5 mg USD 158 In-stock
Estimated Time of Arrival: December 31
10 mg USD 269 In-stock
Estimated Time of Arrival: December 31
20 mg USD 457 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of Liensinine Diperchlorate:

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Description

Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].

Molecular Weight

811.66

Formula

C37H44Cl2N2O14

CAS No.
SMILES

O=Cl(=O)(O)=O.CN1[[email protected]@H](C2=CC(OC3=CC(C[[email protected]@H]4C5=CC(OC)=C(OC)C=C5CCN4C)=CC=C3O)=C(OC)C=C2CC1)CC6=CC=C(O)C=C6.O=Cl(=O)(O)=O

Structure Classification
Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (77.00 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2320 mL 6.1602 mL 12.3204 mL
5 mM 0.2464 mL 1.2320 mL 2.4641 mL
10 mM 0.1232 mL 0.6160 mL 1.2320 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (2.56 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (2.56 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (2.56 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.97%

References
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Product Name:
Liensinine Diperchlorate
Cat. No.:
HY-N0485
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