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  4. Nymphaeaceae

Nymphaeaceae

 

Nymphaeaceae (25):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0770
    Isoliensinine 6817-41-0 99.90%
    Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
    Isoliensinine
  • HY-N6857
    Armepavine 524-20-9 99.53%
    Armepavine, found in Nelumbo nucifera, is an orally active NF-κB inhibitor. Armepavine attenuates expression of p-p65, α-SMA, p-JNK1/2, p-ERK1/2, p-p38α stimulated by TNF-α and LPS. Armepavine suppresses NF-κB nuclear translocation, IκBα phosphorylation, and collagen deposition. Armepavine can be used for the research of hepatic fibrosis and leukemia.
    Armepavine
  • HY-N2307A
    Lirinidine 54383-28-7 99.83%
    Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research.
    Lirinidine
  • HY-121793
    Roemerine 548-08-3 99.89%
    Roemerine is an alkaloid that has been identified from the leaves of Fibraurea recisa Pierre. Roemerine exhibits antibacterial, anticancer, and antidepressant activities, can reverse the multidrug resistance phenotype in cultured cells, and exerts antibacterial effects by regulating the cAMP signaling pathway. Additionally, Roemerine influences neuronal activity by increasing BDNF protein expression and modulating the serotonergic and glutamatergic systems. Roemerine holds promise for research in the fields of cancer, infections, and neurological diseases.
    Roemerine
  • HY-N0485
    Liensinine Diperchlorate 5088-90-4 99.96%
    Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.
    Liensinine Diperchlorate
  • HY-N2129A
    N-Nornuciferine hydrochloride 58546-00-2
    N-Nornuciferine hydrochloride is an orally active, blood-brain barrier-permeable CYP2D6 inhibitor, with an IC50 of 3.76 μM and a Ki of 2.34 μM against human CYP2D6. N-Nornuciferine hydrochloride also acts as a BChE inhibitor, showing an IC50 of 5.6 μM in mice. N-Nornuciferine hydrochloride can be used in the research of neurological-related diseases.
    N-Nornuciferine hydrochloride
  • HY-N2307B
    (R)-Lirinidine 37082-15-8
    (R)-Lirinidine ((-)-Lirinidine) is an aporphine-type alkaloid found in the flower buds and leaves of Nelumbo nucifera. (R)-Lirinidineand inhibits melanogenesis with an IC50 of 19.3 μM. (R)-Lirinidine exerts cytotoxic effects at 100 μM.
    (R)-Lirinidine
  • HY-N17317
    Isostrictiniin 1801746-41-7
    Isostrictiniin (ITN) is a polyphenolic compound isolated from Nymphaea candida. It upregulates the expression of Nrf2 and HO-1, while downregulating the expression of Keap1. Isostrictiniin reduces the phosphorylation levels of JNK, ERK1/2, p38, IκBα, and NF-κB p65. Isostrictiniin decreases the levels of pro-inflammatory mediators (IL-1β, IL-6, TNF-α, PGE2). Isostrictiniin alleviates LPS-induced acute lung injury and exerts protective effects against acute alcoholic liver injury. Additionally, isostrictiniin exhibits anti-inflammatory, antioxidant, and anti-fibrotic activities.
    Isostrictiniin
  • HY-N2129
    N-Nornuciferine 4846-19-9 99.94%
    N-Nornuciferine is an orally active, blood-brain barrier-permeable CYP2D6 inhibitor, with an IC50 of 3.76 μM and a Ki of 2.34 μM against human CYP2D6. N-Nornuciferine also acts as a BChE inhibitor, showing an IC50 of 5.6 μM in mice. N-Nornuciferine can be used in the research of neurological-related diseases.
    N-Nornuciferine
  • HY-N4309A
    Lotusine hydroxide 3721-76-4 99.56%
    Lotusine hydroxide is an orally active signaling pathway modulator and enzyme inhibitor, with an IC50 of 30.60 μg/mL against α-amylase and an IC50 of 36.15 μg/mL against α-glucosidase. Lotusine hydroxide inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine hydroxide induces apoptosis, triggers G0/G1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine hydroxide reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine hydroxide is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder.
    Lotusine hydroxide
  • HY-N7512
    Asimilobine 6871-21-2 99.9%
    Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity.
    Asimilobine
  • HY-N17735
    (R)-1,2-Dihydroxyaporphine 3175-79-9
    (R)-1,2-Dihydroxyaporphine (Compound M1) is a metabolite of Nuciferine (HY-N0049) and is easily excreted through urine and feces.
    (R)-1,2-Dihydroxyaporphine
  • HY-N17730
    Kaempferol-3-O-β-D-glucuronopyranosyl methylester 64290-92-2
    Kaempferol-3-O-β-D-glucuronopyranosyl methylester (Kaempferol 3-(6-methylglucuronide)) is a flavonoid. Kaempferol-3-O-β-D-glucuronopyranosyl methylester can be isolated from dried Nelumbo nucifera stamens. Kaempferol-3-O-β-D-glucuronopyranosyl methylester shows antioxidant activities.
    Kaempferol-3-O-β-D-glucuronopyranosyl methylester
  • HY-N6077
    Thalidezine 18251-36-0
    Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention .
    Thalidezine
  • HY-N9383
    6''-Acetylhyperin 72659-75-7
    6''-Acetylhyperin is a natural phenolic compounds that could be found in Nymphaea odorata.
    6''-Acetylhyperin
  • HY-N7971
    2-Hydroxy-1-Methoxyaporphine 33770-27-3 99.98%
    2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning.
    2-Hydroxy-1-Methoxyaporphine
  • HY-N7655
    7-O-Methylbiochanin A 34086-51-6 98.83%
    7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos.
    7-O-Methylbiochanin A
  • HY-N17338
    Nupharamine 17812-38-3
    Nupharamine ((-)-Nupharamine) is an alkaloid. Nupharamine can be isolated from the root of Nuphar japonicum DC.
    Nupharamine
  • HY-N0770R
    Isoliensinine (Standard) 6817-41-0
    Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
    Isoliensinine (Standard)
  • HY-N10337
    Norjuziphine 74119-87-2
    Norjuziphine ((-)-Norjuziphine) is an alkaloid found in the lotus flower (Nelumbo nucifera). Norjuziphine inhibits the melanogenesis of murine B16 melanoma 4A5 cells stimulated by Theophylline (HY-B0809) (IC50=14.4 μM). Norjuziphine is promising for research of skin whitening and related skin pigmentation diseases.
    Norjuziphine