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Cat. No.: HY-N21517

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(S)-Higenamine 4'-O-beta-D-glucoside

Name: (S)-Higenamine 4'-O-beta-D-glucoside
Brand: MedChemExpress
SKU: HY-N21517
Availability: PreOrder

(Synonyms: (S)-Norcocalurine 4′-O-glucoside)

(S)-Higenamine 4'-O-beta-D-glucoside ((S)-Norcocalurine 4′-O-glucoside) is the S-isomer of Higenamine 4'-O-beta-D-glucoside. Higenamine 4'-O-beta-D-glucoside is a β2-adrenergic receptor-targeted agonist that induces glucose uptake and regulates blood glucose levels. (S)-Higenamine 4'-O-beta-D-glucoside can be used in the research of type 2 diabetes.

For research use only. We do not sell to patients.

CAS No.: 1440545-91-4
Formula: C₂₂H₂₇NO₈
Molecular Weight:433.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S)-Higenamine 4'-O-beta-D-glucoside Chemical Structure

CAS No.: 1440545-91-4

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Biological Activity

Description

All Adrenergic Receptor Isoforms :

In Vitro

Higenamine 4'-O-beta-D-glucoside (0.5-100 μM; 4 h) promotes glucose uptake in differentiated L6 myotubes in a concentration-dependent manner^[1].
Higenamine 4'-O-beta-D-glucoside (10 μM; 4 h) enhances glucose uptake in differentiated L6 myotubes via a β₂-adrenergic receptor-mediated pathway, and this process is independent of the PI3K and AMPK signaling pathways^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1440545-91-4
Molecular Weight 433.45
Formula C₂₂H₂₇NO₈
SMILES

OC(C=C(CCN1)C([C@H]1CC2=CC=C(C=C2)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=C4)=C4O
Synonyms

(S)-Norcocalurine 4′-O-glucoside
Structure Classification
- Alkaloids
- Isoquinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kato E, et al. Higenamine 4'-O-β-d-glucoside in the lotus plumule induces glucose uptake of L6 cells through β2-adrenergic receptor. Bioorg Med Chem. 2015 Jul 1;23(13):3317-21.
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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(S)-Higenamine 4'-O-beta-D-glucoside

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(S)-Higenamine 4'-O-beta-D-glucoside

All Adrenergic Receptor Isoforms

Biological Activity

Description

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S)-Higenamine 4'-O-beta-D-glucoside Related Classifications

HY-N21517 Related Classifications

Bioz

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