2. Natural Products
  3. Plants
  4. Nymphaeaceae
  5. Nelumbo nucifera Gaertn.

Nelumbo nucifera Gaertn.

Synonyms: lotus

Nelumbo nucifera Gaertn. (22):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0770
    Isoliensinine 6817-41-0 99.90%
    Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
    Isoliensinine
  • HY-N6857
    Armepavine 524-20-9 99.53%
    Armepavine, found in Nelumbo nucifera, is an orally active NF-κB inhibitor. Armepavine attenuates expression of p-p65, α-SMA, p-JNK1/2, p-ERK1/2, p-p38α stimulated by TNF-α and LPS. Armepavine suppresses NF-κB nuclear translocation, IκBα phosphorylation, and collagen deposition. Armepavine can be used for the research of hepatic fibrosis and leukemia.
    Armepavine
  • HY-N2307A
    Lirinidine 54383-28-7 99.83%
    Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research.
    Lirinidine
  • HY-121793
    Roemerine 548-08-3 99.89%
    Roemerine is an alkaloid that has been identified from the leaves of Fibraurea recisa Pierre. Roemerine exhibits antibacterial, anticancer, and antidepressant activities, can reverse the multidrug resistance phenotype in cultured cells, and exerts antibacterial effects by regulating the cAMP signaling pathway. Additionally, Roemerine influences neuronal activity by increasing BDNF protein expression and modulating the serotonergic and glutamatergic systems. Roemerine holds promise for research in the fields of cancer, infections, and neurological diseases.
    Roemerine
  • HY-N0485
    Liensinine Diperchlorate 5088-90-4 99.96%
    Liensinine Diperchlor​ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor​ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor​ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.
    Liensinine Diperchlorate
  • HY-N2129A
    N-Nornuciferine hydrochloride 58546-00-2
    N-Nornuciferine hydrochloride is an orally active, blood-brain barrier-permeable CYP2D6 inhibitor, with an IC50 of 3.76 μM and a Ki of 2.34 μM against human CYP2D6. N-Nornuciferine hydrochloride also acts as a BChE inhibitor, showing an IC50 of 5.6 μM in mice. N-Nornuciferine hydrochloride can be used in the research of neurological-related diseases.
    N-Nornuciferine hydrochloride
  • HY-N2307B
    (R)-Lirinidine 37082-15-8
    (R)-Lirinidine ((-)-Lirinidine) is an aporphine-type alkaloid found in the flower buds and leaves of Nelumbo nucifera. (R)-Lirinidineand inhibits melanogenesis with an IC50 of 19.3 μM. (R)-Lirinidine exerts cytotoxic effects at 100 μM.
    (R)-Lirinidine
  • HY-N17735
    (R)-1,2-Dihydroxyaporphine 3175-79-9
    (R)-1,2-Dihydroxyaporphine (Compound M1) is a metabolite of Nuciferine (HY-N0049) and is easily excreted through urine and feces.
    (R)-1,2-Dihydroxyaporphine
  • HY-N2129
    N-Nornuciferine 4846-19-9 99.94%
    N-Nornuciferine is an orally active, blood-brain barrier-permeable CYP2D6 inhibitor, with an IC50 of 3.76 μM and a Ki of 2.34 μM against human CYP2D6. N-Nornuciferine also acts as a BChE inhibitor, showing an IC50 of 5.6 μM in mice. N-Nornuciferine can be used in the research of neurological-related diseases.
    N-Nornuciferine
  • HY-N4309A
    Lotusine hydroxide 3721-76-4 99.56%
    Lotusine hydroxide is an orally active signaling pathway modulator and enzyme inhibitor, with an IC50 of 30.60 μg/mL against α-amylase and an IC50 of 36.15 μg/mL against α-glucosidase. Lotusine hydroxide inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR, Akt and ERK. Lotusine hydroxide induces apoptosis, triggers G0/G1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine hydroxide reduces lipid peroxidation and increases the activities of SOD, CAT and GPx. Lotusine hydroxide is applicable to researches related to non-small cell lung cancer, type 2 diabetes and autism spectrum disorder.
    Lotusine hydroxide
  • HY-N7512
    Asimilobine 6871-21-2 99.9%
    Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity.
    Asimilobine
  • HY-N17730
    Kaempferol-3-O-β-D-glucuronopyranosyl methylester 64290-92-2
    Kaempferol-3-O-β-D-glucuronopyranosyl methylester (Kaempferol 3-(6-methylglucuronide)) is a flavonoid. Kaempferol-3-O-β-D-glucuronopyranosyl methylester can be isolated from dried Nelumbo nucifera stamens. Kaempferol-3-O-β-D-glucuronopyranosyl methylester shows antioxidant activities.
    Kaempferol-3-O-β-D-glucuronopyranosyl methylester
  • HY-N6077
    Thalidezine 18251-36-0
    Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention .
    Thalidezine
  • HY-N7971
    2-Hydroxy-1-Methoxyaporphine 33770-27-3 99.98%
    2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning.
    2-Hydroxy-1-Methoxyaporphine
  • HY-N7655
    7-O-Methylbiochanin A 34086-51-6 98.83%
    7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos.
    7-O-Methylbiochanin A
  • HY-N0770R
    Isoliensinine (Standard) 6817-41-0
    Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells.
    Isoliensinine (Standard)
  • HY-N10337
    Norjuziphine 74119-87-2
    Norjuziphine ((-)-Norjuziphine) is an alkaloid found in the lotus flower (Nelumbo nucifera). Norjuziphine inhibits the melanogenesis of murine B16 melanoma 4A5 cells stimulated by Theophylline (HY-B0809) (IC50=14.4 μM). Norjuziphine is promising for research of skin whitening and related skin pigmentation diseases.
    Norjuziphine
  • HY-N7462
    Norarmepavine 3195-01-5
    Norarmepavine is a Alkaloids product that can be isolated from the stems of Nelumbo nucifera..
    Norarmepavine
  • HY-N6857R
    Armepavine (Standard) 524-20-9
    Armepavine (Standard) is the analytical standard of Armepavine. This product is intended for research and analytical applications. Armepavine, an active compound from Nelumbo nucifera, exerts not only anti-inflammatory effects on human peripheral blood mononuclear cells, but also immunosuppressive effects on T lymphocytes and on lupus nephritic mice. Armepavine inhibits TNF-α-induced MAPK and NF-κB signaling cascades.
    Armepavine (Standard)
  • HY-N13111
    Neoliensinine
    Neoliensinine is a benzylisoquinoline that effectively inhibits KCl (124 mM)-induced contraction of isolated mesenteric vascular smooth muscle (MVSM) with an IC50 value of 2.407 μM. Neoliensinine can be isolated from the embryo of Nelumbo nucifera Gaertn., a traditional Chinese medicine.
    Neoliensinine