(R)-Lirinidine
(R)-Lirinidine ((-)-Lirinidine) is an aporphine-type alkaloid found in the flower buds and leaves of Nelumbo nucifera. (R)-Lirinidineand inhibits melanogenesis with an IC50 of 19.3 μM. (R)-Lirinidine exerts cytotoxic effects at 100 μM.
For research use only. We do not sell to patients.
- CAS No.: 37082-15-8
- Formula: C18H19NO2
- Molecular Weight:281.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
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| B16-4A5 | IC50 |
19.3 μM
Compound: 7, 5-demethylnuciferine
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Inhibition of melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometry
Inhibition of melanogenesis in mouse B16-4A5 cells after 72 hrs by spectrophotometry
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[PMID: 23270663] |
(R)-Lirinidine (Compound 7) (3-100 μM; 72 h) potently inhibits melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells with an IC50 of 19.3 μM, and exhibits cytotoxicity at 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 37082-15-8
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Molecular Weight 281.35
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Formula C18H19NO2
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SMILES
OC1=C(OC)C=C2CCN(C)[C@]3([H])CC4=CC=CC=C4C1=C23
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Synonyms
(-)-Lirinidine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-Lirinidine Related Classifications
HY-N2307B Related Classifications
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