6817-41-0
Chemical Structure
Isoliensinine
- CAS No.: 6817-41-0
- Formula:C37H42N2O6
- Molecular Weight:610.74
IUPAC Name: (R)-1-(4-hydroxy-3-(((R)-6-methoxy-1-(4-methoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)oxy)benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol
InChIKey: AJPXZTKPPINUKN-FIRIVFDPSA-N
SMILES: OC1=CC2=C(C=C1OC)CCN(C)[C@@H]2CC3=CC=C(O)C(OC4=CC5=C(C=C4OC)CCN(C)[C@@H]5CC6=CC=C(OC)C=C6)=C3
Biological Activity: Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells[1][2].
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Isoliensinine | 99.90% | Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells. | ||||||||||||||||||||
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Isoliensinine (Standard) | ≥98% | Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from the seed embryo of Nelumbo nucifera, with anti-oxidant and anti-inflammatory and anti-cancer activities. Isoliensinine induces apoptosis in triple-negative human breast cancer cells. | ||||||||||||||||||||
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Similarity Score 0.94
HY-N0221RDaurisoline (Standard) -
Similarity Score 0.93
HY-N0441RNeferine (Standard) -
Similarity Score 0.91
HY-N1928Dauricinoline -
Similarity Score 0.91
HY-N2104Daurinoline -
Similarity Score 0.91
HY-N0484Liensinine -
Similarity Score 0.90
HY-N9338Guattegaumerine -
Similarity Score 0.88
HY-N0220Dauricine -
Similarity Score 0.84
HY-N2612O-Methyldauricine -
Similarity Score 0.84
HY-N0485Liensinine Diperchlorate -
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References
- [1]. Jun-hua Xiao, et al. Effects of isoliensinine on proliferation of porcine coronary arterial smooth muscle cells induced by phenylephrine. Yao Xue Xue Bao. 2005 Feb;40(2):105-10. [Content Brief]
- [2]. Zhang X, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015 Jul 29;5:12579. [Content Brief]
