1. Alkaloids
  2. Guattegaumerine

Guattegaumerine 

Cat. No.: HY-N9338
Handling Instructions

Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities.

For research use only. We do not sell to patients.

Guattegaumerine Chemical Structure

Guattegaumerine Chemical Structure

CAS No. : 21446-35-5

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Description

Guattegaumerine is a bisbenzylisoquinoline alkaloid with antimitotic, cytotoxic and neuroprotective activities[1].

In Vitro

Guattegaumerine (1.25-6.25 μM; 24 hours; 30 min before exposure to serum-starvation+H2O2) significantly increases cell viability at 1.25 and 2.5μM; and guattegaumerine pretreatment significantly inhibits LDH efflux[1].
Guattegaumerine (2.5 μM; 24 hours; 30 min before exposure to serum-starvation+H2O2) markedly reduces the oxidative stress-induced apoptosis in rat cortical neurons when compares with the control group[1].
Guattegaumerine (1.25-2.5 μM; 24 hours; 30 min before exposure to serum-starvation+H2O2) decreases H2O2 and KCl induced Ca[2+]i increase in cortical neurons[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

596.71

Formula

C₃₆H₄₀N₂O₆

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Guattegaumerine
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