1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. JNK
  4. JNK Isoform

JNK

 

JNK Related Products (40):

Cat. No. Product Name Effect Purity
  • HY-18982
    Anisomycin
    Activator 99.44%
    Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
  • HY-N0431
    Astragaloside IV
    Inhibitor ≥98.0%
    Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
  • HY-B0239
    Chloramphenicol
    Activator 99.82%
    Chloramphenicol is an orally active, potent and broad-spectrum antibiotic.
  • HY-107738
    Guggulsterone
    Activator 99.83%
    Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii.
  • HY-N2149
    Tomatidine
    Inhibitor ≥98.0%
    Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling.
  • HY-N0044
    Ginsenoside Re
    Inhibitor 98.15%
    Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng.
  • HY-N0047
    Polyphyllin I
    Activator 99.61%
    Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity.
  • HY-P0069
    D-JNKI-1
    Inhibitor 99.07%
    D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK.
  • HY-107597
    SU3327
    Inhibitor 98.03%
    SU3327 is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM.
  • HY-13022
    CC-401 hydrochloride
    Inhibitor 99.46%
    CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
  • HY-12829
    SR-3306
    Inhibitor 99.0%
    SR-3306 is a selective, potent, highly brain penetrant JNK inhibitor.
  • HY-10366
    BI-78D3
    Inhibitor 99.49%
    BI-78D3 functions as a substrate competitive inhibitor of JNK, inhibit the JNK kinase activity (IC50=280 nM).
  • HY-P0069A
    L-JNKI-1
    Inhibitor
    L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK.
  • HY-N0809
    Sesamolin
    Inhibitor 99.78%
    Sesaminol, isolated from Sesamum indicum, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect.
  • HY-100538A
    DTP3 TFA
    Inhibitor 98.03%
    DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
  • HY-N7110
    6-Hydroxyflavone
    99.95%
    6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity.
  • HY-N1504
    Loureirin B
    Inhibitor 99.16%
    Loureirin B, a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of plasminogen activator inhibitor-1 (PAI-1), with an IC50 of 26.10 μM; Loureirin B also inhibits KATP, the phosphorylation of ERK and JNK, and has anti-diabetic activity.
  • HY-N2149A
    Tomatidine hydrochloride
    Inhibitor ≥98.0%
    Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling.
  • HY-107599
    AEG3482
    Inhibitor 99.95%
    AEG3482 is a potent antiapoptotic compound that inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70).
  • HY-N1966
    (E)-Osmundacetone
    Inhibitor ≥99.0%
    (E)-Osmundacetone is the isomer of Osmundacetone.