1. Anti-infection
    Metabolic Enzyme/Protease
  2. HIV
    HIV Protease

Saquinavir (Synonyms: Ro 31-8959)

Cat. No.: HY-17007 Purity: 99.91%
Handling Instructions

Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy.

For research use only. We do not sell to patients.
Saquinavir Chemical Structure

Saquinavir Chemical Structure

CAS No. : 127779-20-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 73 In-stock
10 mg USD 66 In-stock
50 mg USD 252 In-stock
100 mg USD 396 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of Saquinavir:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. IC50 Value: Target: HIV Protease Saquinavir is a protease inhibitor. Proteases are enzymes that cleave protein molecules into smaller fragments. HIV protease is vital for both viral replication within the cell and release of mature viral particles from an infected cell. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases.Studies have also looked at Saquinavir as a possible anti-cancer agent.

Clinical Trial
References
Molecular Weight

670.84

Formula

C₃₈H₅₀N₆O₅

CAS No.

127779-20-8

SMILES

O=C(N[[email protected]@H](CC(N)=O)C(N[[email protected]@H](CC1=CC=CC=C1)[[email protected]](O)CN2[[email protected]](C(NC(C)(C)C)=O)C[[email protected]@](CCCC3)([H])[[email protected]@]3([H])C2)=O)C4=NC5=CC=CC=C5C=C4

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 99.91%

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Product Name:
Saquinavir
Cat. No.:
HY-17007
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