633-66-9
Chemical Structure
Berberine sulfate
Synonym(s): Natural Yellow 18 sulfate
- CAS No.: 633-66-9
- Formula:C20H19NO8S
- Molecular Weight:433.43
IUPAC Name: 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium hydrogen sulfate
InChIKey: JISRTQBQFQMSLG-UHFFFAOYSA-M
SMILES: COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C=C2C=C1.O=S(O)([O-])=O
Biological Activity: Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability[1][2].
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Berberine sulfate | 99.23% | Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability. | ||||||||||||||||||||
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Berberine sulfate (Standard) | 98.89% | Berberine (sulfate) (Standard) is the analytical standard of Berberine (sulfate). This product is intended for research and analytical applications. Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability. | ||||||||||||||||||||
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Similarity Score 0.91
HY-N0716Berberine -
Similarity Score 0.91
HY-18258Berberine chloride -
Similarity Score 0.91
HY-17577RBerberine chloride hydrate (Standard) -
Similarity Score 0.81
HY-125850Berberrubine chloride -
Similarity Score 0.80
HY-N0430ACoptisine Sulfate -
Similarity Score 0.76
HY-N0226AEpiberberine chloride -
Similarity Score 0.76
HY-N0226Epiberberine -
Similarity Score 0.75
HY-N0592ADemethyleneberberine chloride -
Similarity Score 0.75
HY-N0592Demethyleneberberine -
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References
- [1]. Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62. [Content Brief]
- [2]. Cui HX, et al. Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability. Molecules. 2018 Dec 28;24(1):103. [Content Brief]
