Berberine sulfate (Standard)
Based on 1 Customer Validation
Berberine (sulfate) (Standard) is the analytical standard of Berberine (sulfate). This product is intended for research and analytical applications. Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability[1][2].
For research use only. We do not sell to patients.
- CAS No.: 633-66-9
- Formula: C20H19NO8S
- Molecular Weight:433.43
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Storage:
4°C, sealed and dry storage, away from light and moisture
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 633-66-9
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Appearance Solid
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Molecular Weight 433.43
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Formula C20H19NO8S
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Color Light yellow to yellow
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SMILES
COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C=C2C=C1.O=S(O)([O-])=O
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Synonyms
Natural Yellow 18 sulfate (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed and dry storage, away from light and moisture
Purity & Documentation
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62. [Content Brief]
[2]. Cui HX, et al. Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability. Molecules. 2018 Dec 28;24(1):103. [Content Brief]
[3]. Boberek JM, et al., Genetic evidence for inhibition of bacterial division protein FtsZ by berberine. PLoS One. 2010 Oct 29;5(10):e13745. [Content Brief]
[4]. Remppis A, et al., Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. Mediators Inflamm. 2010;2010:194896. [Content Brief]
[5]. Bae J, et al., Berberine protects 6-hydroxydopamine-induced human dopaminergic neuronal cell death through the induction of heme oxygenase-1. Mol Cells. 2013 Feb;35(2):151-7. [Content Brief]
[6]. Ye Y, et al., Efficacy and Safety of Berberine Alone for Several Metabolic Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Front Pharmacol. 2021 Apr 26;12:653887. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Berberine sulfate (Standard) Related Classifications
HY-N0716BR Related Classifications
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- Berberine sulfate (Standard)
- 633-66-9
- Natural Yellow 18 sulfate (Standard)
- Reference Standards
- Antibiotic
- Topoisomerase
- Autophagy
- Bacterial
- Reactive Oxygen Species (ROS)
- Parasite
- Apoptosis
- PI3K
- Akt
- Caspase
- JNK
- AP-1
- NF-κB
- diabetes mellitus
- type II diabetes
- Alzheimer’s disease
- Parkinson’s disease
- arrhythmia
- atherosclerosis
- hyperlipidemia
- hypertension
- myocarditis
- cardiomyopathy
- heart failure
- RAW264.7
- dopamine
- Inhibitor
- inhibitor
- inhibit