1. NF-κB
    PI3K/Akt/mTOR
    Epigenetics
  2. NF-κB
    AMPK
  3. Demethyleneberberine

Demethyleneberberine 

Cat. No.: HY-N0592 Purity: >98.0%
Handling Instructions

Demethyleneberberine is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine could serve as a AMPK activator for treating non-alcoholic fatty liver disease (NAFLD).

For research use only. We do not sell to patients.

Demethyleneberberine Chemical Structure

Demethyleneberberine Chemical Structure

CAS No. : 25459-91-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 121 In-stock
Estimated Time of Arrival: December 31
1 mg USD 65 In-stock
Estimated Time of Arrival: December 31
5 mg USD 170 In-stock
Estimated Time of Arrival: December 31
10 mg USD 290 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Demethyleneberberine is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine could serve as a AMPK activator for treating non-alcoholic fatty liver disease (NAFLD)[1][2][3].

Molecular Weight

324.35

Formula

C₁₉H₁₈NO₄+

CAS No.

25459-91-0

SMILES

COC1=C(OC)C2=C[N+]3=C(C4=CC(O)=C(O)C=C4CC3)C=C2C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References

Purity: >98.0%

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Keywords:

DemethyleneberberineNF-κBAMPKNuclear factor-κBNuclear factor-kappaBAMP-activated protein kinaseInhibitorinhibitorinhibit

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Demethyleneberberine
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