1. Signaling Pathways
  2. Epigenetics
    JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
    Stem Cell/Wnt
  3. JAK
  4. JAK Isoform

JAK

 

JAK Related Products (69):

Cat. No. Product Name Effect Purity
  • HY-N0201
    Atractylenolide I
    99.83%
    Atractylenolide I is a sesquiterpene derived from the rhizome of Atractylodes macrocephala, possesses diverse bioactivities, such as neuroprotective, anti-allergic, anti-inflammatory and anticancer properties.
  • HY-102055
    JAK2 JH2 Tracer
    ≥98.0%
    JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd of value 0.2 μM.
  • HY-N2515
    Ginsenoside Rk1
    Inhibitor 99.90%
    Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures.
  • HY-50856A
    Ruxolitinib (S enantiomer)
    Inhibitor 99.77%
    Ruxolitinib S enantiomer is the S-enantiomer of Ruxolitinib.
  • HY-103018
    Gusacitinib
    Inhibitor 99.41%
    Gusacitinib (ASN-002) is an orally active and potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
  • HY-150096
    Zasocitinib
    Inhibitor ≥98.0%
    Zasocitinib (NDI-034858) is a TYK2 inhibitor, target TYK2 JH2 domain with binding constant Kd of <200 pM.
  • HY-111749
    JAK-IN-4
    Inhibitor
    JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.
  • HY-109148
    Izencitinib
    Inhibitor ≥98.0%
    Izencitinib (TD-1473) is an orally active, non-selective and gut-restricted JAK inhibitor.
  • HY-100544
    FLLL32
    Inhibitor 99.78%
    FLLL32, a synthetic analog of curcumina, is a JAK2/STAT3 dual inhibitor with anti-tumor activity.
  • HY-N0705
    Curculigoside
    Inhibitor 99.73%
    Curculigoside is the main saponin in C.
  • HY-100538
    DTP3
    Inhibitor 99.43%
    DTP3 TFA is a potent and selective GADD45β/MKK7 inhibitor.
  • HY-111471A
    JAK-IN-5 hydrochloride
    Inhibitor 99.54%
    JAK-IN-5 hydrochloride is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
  • HY-18303
    AMG-47a
    Inhibitor 98.72%
    AMG-47a is a potent and orally active lymphocyte-specific protein tyrosine kinase (Lck) inhibitor, with an IC50 of 0.2 nM.
  • HY-N2409
    Delphinidin chloride
    Inhibitor ≥98.0%
    Delphinidin chloride, an anthocyanidin, is isolated from berries and red wine.
  • HY-109178
    Ifidancitinib
    Inhibitor 98.05%
    Ifidancitinib (ATI-50002) is a potent and selective inhibitor of JAK kinases 1/3.
  • HY-107459
    (E/Z)-AG490
    Inhibitor
    (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers.
  • HY-N7452
    Coumermycin A1
    Activator ≥98.0%
    Coumermycin A1 is a JAK2 signal activator.
  • HY-109182
    Lorpucitinib
    Inhibitor 99.97%
    Lorpucitinib is a Gut-Restricted JAK Inhibitor for the research of Inflammatory Bowel Disease.
  • HY-111471
    JAK-IN-5
    Inhibitor
    JAK-IN-5 is an inhibitor of JAK extracted from patent US20170121327A1, compound example 283.
  • HY-10412
    CEP-1347
    Inhibitor ≥98.0%
    CEP-1347 is an inhibitor of the JNK/SAPK pathway with neuroprotective effects.