941685-37-6
941685-37-6
Chemical Structure
Ruxolitinib (S enantiomer)
Synonym(s): S-Ruxolitinib; S-INCB18424
- CAS No.: 941685-37-6
- Formula:C17H18N6
- Molecular Weight:306.37
IUPAC Name: (S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
InChIKey: HFNKQEVNSGCOJV-HNNXBMFYSA-N
SMILES: N#CC[C@@H](C1CCCC1)N2N=CC(C3=NC=NC4=C3C=CN4)=C2
Biological Activity: Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ruxolitinib (S enantiomer) | 99.64% | Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor. | ||||||||||||||||||||
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References
- [1]. Hye Kyung Lee, et al. JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells. Commun Biol. 2021 Jun 2;4(1):654. [Content Brief]
- [2]. Lorena Arranz, et al. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature. 2014 Aug 7;512(7512):78-81. [Content Brief]
Keywords
