2. Apoptosis
  3. Apoptosis
  4. Jolkinolide B

Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells.

For research use only. We do not sell to patients.

Jolkinolide B Chemical Structure

Jolkinolide B Chemical Structure

CAS No. : 37905-08-1

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1 mg USD 75 In-stock
5 mg USD 180 In-stock
10 mg USD 280 In-stock
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Jolkinolide B Related Antibodies

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Description

Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, is known to induce apoptosis in cancer cells[1].

IC50 & Target

IC50: apoptosis[1]
Molecular Weight

330.42

Formula

C20H26O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@]1([H])CC2)(CCCC1(C)C)[C@@]([C@@H]3[C@@]4(O5)O3)([H])[C@@]62[C@@H](C4=C(C)C5=O)O6
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (25.21 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0265 mL 15.1323 mL 30.2645 mL
5 mM 0.6053 mL 3.0265 mL 6.0529 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0265 mL 15.1323 mL 30.2645 mL 75.6613 mL
5 mM 0.6053 mL 3.0265 mL 6.0529 mL 15.1323 mL
10 mM 0.3026 mL 1.5132 mL 3.0265 mL 7.5661 mL
15 mM 0.2018 mL 1.0088 mL 2.0176 mL 5.0441 mL
20 mM 0.1513 mL 0.7566 mL 1.5132 mL 3.7831 mL
25 mM 0.1211 mL 0.6053 mL 1.2106 mL 3.0265 mL
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Jolkinolide B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Jolkinolide B37905-08-1ApoptosiscancerhumanleukemicU937cellsInhibitorinhibitorinhibit

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