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IAP

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Cat. No. Compare Product Name Species Source
  • HY-P700682

    CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6

    Rhesus Macaque;Cynomolgus HEK293
    CD47 is a leukocyte surface antigen, and high expression of CD47 helps tumors escape. CD47 inhibition leads to the activation of CD103+ dendritic cells, which leads to the recruitment and activation of natural killer cells and inhibits cancer development. CD47 Protein, Cynomolgus/Rhesus Macaque (HEK293, C-His) is the recombinant Rhesus Macaque, cynomolgus-derived CD47 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD47 Protein, Cynomolgus/Rhesus Macaque (HEK293, C-His) is 123 a.a., with molecular weight of 30-43 kDa.
  • HY-P78095

    CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, His-Avi) is 121 a.a., with molecular weight of 45-55 kDa.
  • HY-P74289A

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Mouse HEK293
    The CD47 protein, also known as integrin-associated protein (IAP), is an immune checkpoint protein. CD47 binds to membrane integrins and binds ligands platelet reaction-protein-1 (TSP-1) and signal regulatory protein alpha (SIRP伪). CD47 is a potential therapeutic target for some cancers and is also used to treat pulmonary fibrosis. CD47 Protein, Mouse (HEK293, Tag Free) is the recombinant mouse-derived CD47 protein, expressed by HEK293 , with tag free. The total length of CD47 Protein, Mouse (HEK293, Tag Free) is 122 a.a., with molecular weight of ~27-34 kDa.
  • HY-P700653

    IAP; Akp2; ALPL; APTNAP; AP-TNAP; FLJ40094; FLJ93059; HOPS; MGC161443; TNAP; TNSALP

    Mouse HEK293
    Alkaline Phosphatase/ALPL Protein, vital with phosphatase, metal ion binding, and homodimerization activities, influences BMP stimulus response. Strategically located externally on the plasma membrane, its predicted activity emphasizes cellular functions. Prominent expression in the intestine and testis, especially in duodenum adult (RPKM 2234.3) and small intestine adult (RPKM 1574.5), underscores specific roles in these contexts. Its human orthologs, implicated in inflammatory bowel disease, highlight clinical relevance. Evolutionarily conserved, Alkaline Phosphatase/ALPL shares orthologous counterparts like ALPI in several human genes. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-His labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, C-His) is 481 a.a., with molecular weight of 60-70 kDa.
  • HY-P78094

    CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Fc) is 121 a.a., with molecular weight of 55-65 kDa.
  • HY-P7336

    rHuCD47, His; CD47; MER6; IAP; OA3

    Human HEK293
    CD47 Protein, Human (HEK293, His) is a polypeptide chain with His tag produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.
  • HY-P701266

    CD47; MER6; IAP; OA3

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. FITC-Labeled CD47 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled CD47 protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled CD47 Protein, Human (HEK293, His) is 121 a.a., with molecular weight of 35-45 kDa.
  • HY-P78908

    CD47; MER6; IAP; OA3

    Human HEK293
    FITC-Labeled CD47, an adhesive protein, modulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, impacting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal, and immunoregulation. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor agent in blood pressure regulation, and is crucial for memory formation. CD47's interactions with SIRPA, SIRPG, and FAS/CD95 influence dendritic cell maturation, T-cell activation, apoptosis, and angiogenesis. As a monomer, CD47 intricately participates in diverse cellular and molecular pathways, contributing to physiological and pathological processes. CD47 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293, with C-Avi, C-hFc labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 121 a.a., with molecular weight of 55-66 kDa.
  • HY-P78561

    CD47; MER6; IAP; OA3

    Human HEK293
    FITC-Labeled CD47, an adhesive protein, modulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, impacting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal, and immunoregulation. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor agent in blood pressure regulation, and is crucial for memory formation. CD47's interactions with SIRPA, SIRPG, and FAS/CD95 influence dendritic cell maturation, T-cell activation, apoptosis, and angiogenesis. As a monomer, CD47 intricately participates in diverse cellular and molecular pathways, contributing to physiological and pathological processes. CD47 Protein, Human (Biotinylated, HEK293, mFc-Avi) is the recombinant human-derived CD47 protein, expressed by HEK293, with C-mFc, C-Avi labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, mFc-Avi) is 121 a.a., with molecular weight of 60-66 kDa.
  • HY-P7335

    rHuCD47, Fc Chimera; MER6; IAP; OA3

    Human HEK293
    CD47 Protein, Human (HEK293, Fc) is a polypeptide chain with the C-terminal human IgG1 Fc fragment produced in HEK293 cells. CD47 is a prominent target in cancer immunotherapy.
  • HY-P700394

    Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline Phosphatase

    Human HEK293
    ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, N-His) is the recombinant human-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Human (HEK293, N-His) is 484 a.a., with molecular weight of 55.2 kDa.
  • HY-P700395

    Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline Phosphatase

    Rat HEK293
    The ALPI protein, an alkaline phosphatase enzyme, hydrolyzes phosphate compounds, demonstrating enzymatic activity in breaking down different phosphate molecules. ALPI Protein, Rat (HEK293, His) is the recombinant rat-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Rat (HEK293, His) is 491 a.a., with molecular weight of 55.9 kDa.
  • HY-P78711

    CD47; MER6; IAP; OA3

    Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD47 Protein, Mouse (HEK293, Fc) is 122 a.a., with molecular weight of 60-70 kDa.
  • HY-P7831

    rRhIntegrin-associated protein/CD47, Fc; Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6

    Rhesus Macaque;Cynomolgus HEK293
    CD47 is a leukocyte surface antigen, and high expression of CD47 helps tumors escape. CD47 inhibition leads to the activation of CD103+ dendritic cells, which leads to the recruitment and activation of natural killer cells and inhibits cancer development. CD47 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD47 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD47 Protein, Rhesus Macaque (HEK293, Fc) is 121 a.a., with molecular weight of 60-90 kDa.
  • HY-P70820

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6

    Mouse HEK293
    CD47 Protein, an adhesive multifunctional protein, orchestrates cell-to-cell interactions, serving as a receptor for THBS1 and modulating integrin signaling via heterotrimeric G proteins. It plays a pivotal role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, immunoregulation, and memory formation. CD47, a receptor for SIRPA, influences dendritic cell maturation, inhibits cytokine production, and mediates cell-cell adhesion. Additionally, it modulates pulmonary EDN1 signaling, supports blood pressure in response to THBS1-induced NO signaling, and contributes to memory formation. CD47's role in wound healing, stem cell self-renewal inhibition, and its interactions with THBS1, SIRPA, FAS/CD95, SIRPG, UBQLN1, UBQLN2, and possibly fibrinogen underscore its diverse impact on cellular processes. Existing as a monomer, CD47 exhibits intricate involvement in various cellular pathways. CD47 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293, with C-6*His labeled tag. The total length of CD47 Protein, Mouse (HEK293, His) is 140 a.a., with molecular weight of 30-60 kDa.
  • HY-P72359

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; IAP; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived CD47 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CD47 Protein, Human (Biotinylated, HEK293, Avi-His) is 121 a.a., with molecular weight of 30-55 kDa.
  • HY-P72918

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Mouse HEK293
    The CD47 protein is an adhesive multifunctional protein that coordinates cell-cell interactions, serves as a THBS1 receptor, and regulates integrin signaling through heterotrimeric G proteins. It plays a key role in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cell self-renewal, immune regulation, and memory formation. CD47 Protein, Mouse (Q61735-1, HEK293, His) is the recombinant mouse-derived CD47 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD47 Protein, Mouse (Q61735-1, HEK293, His) is 122 a.a., with molecular weight of 34-44 kDa.
  • HY-P75402

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Rat HEK293
    CD47 protein, acting as a receptor for THBS1 and modulating integrin signaling, facilitates cell-to-cell interactions. It plays roles in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, immunoregulation, and memory formation. CD47 interacts with SIRPA, SIRPG, FAS/CD95, UBQLN1, UBQLN2, and fibrinogen, enhancing adhesion, T-cell proliferation, and activation. It suppresses angiogenesis, regulates wound healing and stem cell self-renewal, and prevents premature elimination of red blood cells. CD47 influences pulmonary endothelin signaling, NO signaling, and blood pressure regulation. It may also contribute to metabolic dysregulation during aging. CD47 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD47 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD47 Protein, Rat (HEK293, Fc) is 122 a.a., with molecular weight of 50-70 kDa.
  • HY-P75401

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Rat HEK293
    CD47 protein, acting as a receptor for THBS1 and modulating integrin signaling, facilitates cell-to-cell interactions. It plays roles in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, immunoregulation, and memory formation. CD47 interacts with SIRPA, SIRPG, FAS/CD95, UBQLN1, UBQLN2, and fibrinogen, enhancing adhesion, T-cell proliferation, and activation. It suppresses angiogenesis, regulates wound healing and stem cell self-renewal, and prevents premature elimination of red blood cells. CD47 influences pulmonary endothelin signaling, NO signaling, and blood pressure regulation. It may also contribute to metabolic dysregulation during aging. CD47 Protein, Rat (HEK293, His) is the recombinant rat-derived CD47 protein, expressed by HEK293, with C-His labeled tag. The total length of CD47 Protein, Rat (HEK293, His) is 122 a.a., with molecular weight of ~23-40 kDa.
  • HY-P74289

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Mouse HEK293
    The CD47 protein, also known as integrin-associated protein (IAP), is an immune checkpoint protein. CD47 binds to membrane integrins and binds ligands platelet reaction-protein-1 (TSP-1) and signal regulatory protein alpha (SIRP伪). CD47 is a potential therapeutic target for some cancers and is also used to treat pulmonary fibrosis. CD47 Protein, Mouse (HEK293, solution) is the recombinant mouse-derived CD47 protein, expressed by HEK293 , with tag free. The total length of CD47 Protein, Mouse (HEK293, solution) is 122 a.a., with molecular weight of ~13.8 kDa.
  • HY-P72917

    Leukocyte Surface Antigen CD47; IAP; CD47; MER6

    Human HEK293
    CD47 is an adhesion protein that regulates integrin signaling through G protein activation and serves as a receptor for thrombospondin THBS1, affecting signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, self-renewal and Immunomodulatory. It regulates pulmonary endothelin EDN1 signaling, acts as a pressor in blood pressure regulation, and is critical for memory formation. CD47 Protein, Human (HEK293) is the recombinant human-derived CD47 protein, expressed by HEK293 , with tag free. The total length of CD47 Protein, Human (HEK293) is 121 a.a., with molecular weight of 35-48 kDa.
  • HY-P72821

    Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline Phosphatase

    Human HEK293
    ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, Fc) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ALPI Protein, Human (HEK293, Fc) is 503 a.a., with molecular weight of 90-95 kDa.
  • HY-P72822

    Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline Phosphatase

    Human HEK293
    ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, His) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-His labeled tag. The total length of ALPI Protein, Human (HEK293, His) is 484 a.a., with molecular weight of ~70-80 kDa.
  • HY-P71692

    Alkaline phosphatase intestinal; Glycerophosphatase; IAP

    Human E. coli
    ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (His) is the recombinant human-derived ALPI protein, expressed by E. coli , with N-His labeled tag. The total length of ALPI Protein, Human (His) is 475 a.a., with molecular weight of ~55.5 kDa.
  • HY-P72240

    Amylin; DAP; Diabetes associated peptide; Diabetes-associated peptide; IAP; IAPP; IAPP_HUMAN; Insulinoma amyloid peptide; Islet amyloid polypeptide diabetes associated peptide, amylin; ; Islet amyloid polypeptide

    Human E. coli
    The IAPP protein selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, affecting glucose metabolism without affecting adipocytes. IAPP interacts with IDE (insulin-degrading enzyme) and insulin (INS) to form homodimers, affecting their fibril formation. IAPP Protein, Human (GST) is the recombinant human-derived IAPP protein, expressed by E. coli , with N-GST labeled tag. The total length of IAPP Protein, Human (GST) is 37 a.a., with molecular weight of ~31.4 kDa.
  • HY-P76824

    Baculoviral IAP repeat-containing protein 2; IAP homolog B; hIAP-2; BIRC2; API1; MIHB; RNF48

    Human E. coli
    The multifunctional cIAP1/HIAP-2 protein serves as a key coordinator affecting caspases, apoptosis, inflammatory signaling, immunity, mitotic kinase signaling, cell proliferation, invasion, and metastasis. As an E3 ubiquitin protein ligase, it complexly regulates NF-kappa-B signaling, acting as both a positive regulator of the classical pathway and a suppressor of non-canonical NF-kappa-B signaling. cIAP1/HIAP-2 Protein, Human (His) is the recombinant human-derived cIAP1/HIAP-2 protein, expressed by E. coli , with C-His labeled tag. The total length of cIAP1/HIAP-2 Protein, Human (His) is 213 a.a., with molecular weight of ~26 kDa.
  • HY-P71717

    Birc5; Api4; IAP4Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; TIAP

    Mouse P. pastoris
    Apoptosis inhibitor 4/Birc5 has the dual effects of promoting cell proliferation and inhibiting apoptosis. As an important component of the chromosomal channel protein complex (CPC), Birc5 coordinates chromosome alignment and segregation during mitosis and cytokinesis. Apoptosis inhibitor 4/Birc5 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Apoptosis inhibitor 4/Birc5 protein, expressed by P. pastoris , with N-His labeled tag. The total length of Apoptosis inhibitor 4/Birc5 Protein, Mouse (P.pastoris, His) is 140 a.a., with molecular weight of ~18.3 kDa.
  • HY-P73485

    E3 ubiquitin-protein ligase XIAP; ILP; IAP-3; XIAP; API3; BIRC4

    Human E. coli
    XIAP protein is a multifunctional regulator that controls apoptosis, inflammation, immunity, copper homeostasis, and various signaling pathways. As a caspase inhibitor, it blocks CASP3 and CASP7 substrate access, keeping CASP9 inactive. XIAP Protein, Human (Avi) is the recombinant human-derived XIAP protein, expressed by E. coli , with C-Avi labeled tag. The total length of XIAP Protein, Human (Avi) is 236 a.a., with molecular weight of ~29.1 kDa.
  • HY-P73537

    E3 ubiquitin-protein ligase XIAP; ILP; IAP-3; XIAP; API3; BIRC4

    Human E. coli
    XIAP protein is a multifunctional regulator that controls apoptosis, inflammation, immunity, copper homeostasis, and various signaling pathways. As a caspase inhibitor, it blocks CASP3 and CASP7 substrate access, keeping CASP9 inactive. XIAP Protein, Human (His) is the recombinant human-derived XIAP protein, expressed by E. coli , with N-His labeled tag. The total length of XIAP Protein, Human (His) is 105 a.a., with molecular weight of ~14.8 kDa.
  • HY-P77769

    Survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha

    Human HEK293
    HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 Survivin Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 Survivin Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Protein, Human (HEK293, His-Avi), has molecular weight of 53-60 kDa.
  • HY-P77770

    Survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha

    Human HEK293
    HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 Survivin Complex Tetramer protein, expressed by HEK293 , with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
  • HY-P700944

    Survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha

    Human HEK293
    HLA-A*0201 MAGE-A4 Complex Protein, a member of the major histocompatibility complex (MHC) class I family, is highlighted. Additionally, the Chimeric HLA-A*0201 WT-1 Complex Tetramer is recognized within the MHC class I family. HLA-A*0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived HLA-A*0201 Survivin Complex protein, expressed by HEK293, with C-Avi, C-His labeled tag. HLA-A*0201 Survivin Complex Protein, Human (Biotinylated, LMLGEFLKL, HEK293, His-Avi), has molecular weight of 55-63 kDa.
  • HY-P77065

    Baculoviral IAP repeat-containing protein 7; KIAP; MLIAP; RNF50

    Human E. coli
    Livin/BIRC7, an apoptotic regulator, orchestrates proapoptotic and anti-apoptotic activities, crucial for apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic function involves inhibiting CASP3, CASP7, and CASP9, alongside E3 ubiquitin-protein ligase activity. Despite being a weak caspase inhibitor, Livin's anti-apoptotic prowess arises from ubiquitinating DIABLO/SMAC, preventing its interference with XIAP/BIRC4-caspase interactions, ensuring cell survival. Livin shields against TNF or chemical-induced apoptosis through MAPK8/JNK1 activation, possibly aided by MAP3K7/TAK1 and TAB1. It inhibits CASP3, blocks pro-CASP9 activation, and promotes NK cell-mediated killing, highlighting its multifaceted regulatory roles. Livin/BIRC7 Protein, Human (His) is the recombinant human-derived Livin/BIRC7 protein, expressed by E. coli, with C-His labeled tag. The total length of Livin/BIRC7 Protein, Human (His) is 298 a.a., with molecular weight of ~35 kDa.
  • HY-P7645

    rHuBIRC5; Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; BIRC5; Survivin; BIRC5

    Human E. coli
    BIRC5 Protein, Human, a protein in the intrinsic apoptotic pathway that interacts with XIAP and DIABLO leading to caspase-3 and caspase-9 inactivation. BIRC5 (survivin) is also involved in stabilizing the microtubule-kinetochore dynamics.
  • HY-P702495

    rHuBIRC5; Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; BIRC5; Survivin; BIRC5

    Human E. coli
    The BIRC5 protein has dual roles in cell proliferation and prevention of apoptosis. It is an important CPC component and guides chromosome alignment and segregation during mitosis. It directs CPC movement, contributes to central spindle organization, and recruits CPC to centromeres. BIRC5 Protein, Human (His-SUMO) is the recombinant human-derived BIRC5 protein, expressed by E. coli , with labeled tag. The total length of BIRC5 Protein, Human (His-SUMO) is 142 a.a., with molecular weight of 32.5 kDa.

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