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  3. PROTAC RAR Degrader-1

PROTAC RAR Degrader-1 

Cat. No.: HY-111844
Handling Instructions

PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).

For research use only. We do not sell to patients.

PROTAC RAR Degrader-1 Chemical Structure

PROTAC RAR Degrader-1 Chemical Structure

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10 mg USD 1600 Get quote

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Description

PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

References
Molecular Weight

902.13

Formula

C₅₀H₇₁N₅O₁₀

SMILES

N[[email protected]@H]([[email protected]@H](C(N[[email protected]@H](CC(C)C)C(NNCCOCCOCCC(NCCCOC1=CC(/C=C/C(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)=O)=CC=C1C(O)=O)=O)=O)=O)O)CC3=CC=CC=C3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
PROTAC RAR Degrader-1
Cat. No.:
HY-111844
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PROTAC RAR Degrader-1

Cat. No.: HY-111844