1. PROTAC
  2. SNIPER
    PROTAC
  3. PROTAC RAR Degrader-1

PROTAC RAR Degrader-1 

Cat. No.: HY-111844
Handling Instructions

PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).

For research use only. We do not sell to patients.

PROTAC RAR Degrader-1 Chemical Structure

PROTAC RAR Degrader-1 Chemical Structure

CAS No. : 1351169-27-1

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

917.14

Formula

C₅₁H₇₂N₄O₁₁

CAS No.

1351169-27-1

SMILES

O=C(O)C1=CC=C(/C=C/C(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)=O)C=C1OCCCNC(COCCOCCOCCNC([[email protected]](CC(C)C)NC([[email protected]@H](O)[C[email protected]](N)CC3=CC=CC=C3)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PROTAC RAR Degrader-1
Cat. No.:
HY-111844
Quantity:

PROTAC RAR Degrader-1

Cat. No.: HY-111844