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Cat. No.: HY-128821

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cIAP1 Ligand-Linker Conjugates 4

Name: cIAP1 Ligand-Linker Conjugates 4
Brand: MedChemExpress
SKU: HY-128821
Availability: PreOrder

(Synonyms: E3 ligase Ligand-Linker Conjugates 42)

cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs.

For research use only. We do not sell to patients.

Formula: C₅₅H₆₇N₅O₁₁
Molecular Weight:974.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

cIAP1 Ligand-Linker Conjugates 4 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs^[1].

IC₅₀ & Target

cIAP1

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 974.15
Formula C₅₅H₆₇N₅O₁₁
SMILES

C[C@H](N(C(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)C)C(N[C@@H](C4CCCCC4)C(N(CCC5)[C@@H]5C(N[C@@H](C(C6=CC=CC=C6)C7=CC=CC=C7)C(NCCOCCOCCOCC(O)=O)=O)=O)=O)=O
Synonyms

E3 ligase Ligand-Linker Conjugates 42
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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cIAP1 Ligand-Linker Conjugates 4

All E3 Ligase Ligand-Linker Conjugates Isoforms