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Cat. No.: HY-128826

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cIAP1 Ligand-Linker Conjugates 10

Name: cIAP1 Ligand-Linker Conjugates 10
Brand: MedChemExpress
SKU: HY-128826
Availability: PreOrder

(Synonyms: E3 ligase Ligand-Linker Conjugates 47)

cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs.

For research use only. We do not sell to patients.

Formula: C₄₈H₆₈N₄O₁₂
Molecular Weight:893.07

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

cIAP1 Ligand-Linker Conjugates 10 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs^[1].

IC₅₀ & Target

cIAP1

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 893.07
Formula C₄₈H₆₈N₄O₁₂
SMILES

CC(C)C[C@H](NC([C@H]([C@@H](CC1=CC=CC=C1)NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)O)=O)C(NCCOCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O
Synonyms

E3 ligase Ligand-Linker Conjugates 47
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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cIAP1 Ligand-Linker Conjugates 10

All E3 Ligase Ligand-Linker Conjugates Isoforms