1. PROTAC
  2. SNIPER
    PROTAC
  3. PROTAC ERα Degrader-2

PROTAC ERα Degrader-2 

Cat. No.: HY-111846
Handling Instructions

PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs).

For research use only. We do not sell to patients.

PROTAC ERα Degrader-2 Chemical Structure

PROTAC ERα Degrader-2 Chemical Structure

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5 mg USD 1100 Get quote
10 mg USD 1600 Get quote

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Description

PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. Maximal ERα degradation at 30 μM concentration in human mammary tumor MCF7 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

References
Molecular Weight

778.98

Formula

C₄₂H₆₂N₆O₈

SMILES

N[[email protected]@H]([[email protected]@H](C(N[[email protected]@H](CC(C)C)C(NNCCOCCOCCNC(CO/N=C1CC[[email protected]]2([H])[[email protected]]\1(C)CC[[email protected]@]3([H])[[email protected]@]2([H])CCC4=C3C=CC(O)=C4)=O)=O)=O)O)CC5=CC=CC=C5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
PROTAC ERα Degrader-2
Cat. No.:
HY-111846
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PROTAC ERα Degrader-2

Cat. No.: HY-111846