1. Signaling Pathways
  2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. ERα Isoform


Cat. No. Product Name Effect Purity
  • HY-14590
    Inhibitor 99.67%
    Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK.
  • HY-100689
    Propyl pyrazole triol
    Agonist 99.11%
    Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist.
  • HY-133017
    Antagonist 99.59%
    SAR439859 (compound 43d) is an orally active, nonsteroidal and selective estrogen receptor degrader (SERD).
  • HY-14933
    Agonist 98.05%
    Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively.
  • HY-103454
    MPP dihydrochloride
    Modulator 99.06%
    MPP dihydrochloride is a potent and selective ER (estrogen receptor) modulator.
  • HY-126109
    (±)-8-Prenylnaringenin, a natural prenylated flavonoid, is a potent phytoestrogen.
  • HY-112611
    Inhibitor ≥98.0%
    H3B-5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist, inactivates both wild-type and mutant ERα by targeting Cys530, with Kis of 1 nM and 0.41 nM, respectively.
  • HY-B1662
    Agonist 99.88%
    Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ.
  • HY-111846
    PROTAC ERα Degrader-2
    Inhibitor 98.88%
    PROTAC ERα Degrader-2 comprises a IAP ligand binding group, a linker and an estrogen receptor α (ERα) binding group.
  • HY-119437
    Inhibitor 99.71%
    FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions.
  • HY-16023
    Acolbifene hydrochloride
    Antagonist 98.48%
    Acolbifene (EM-652) hydrochloride, an active metabolite of EM800, is an orally active, cancer-preventing selective estrogen receptor modulator (SERM).
  • HY-125263
    Inhibitor 99.47%
    OP-1074 is a pure antiestrogen and a selective ER degrader (PA-SERD), shows specific antiestrogenic activity for ERα and ERβ, inhibits 17β-estradiol (E2)-stimulated transcriptional activity with IC50 of 1.6 and 3.2 nM, respectively.
  • HY-16023A
    Antagonist 98.86%
    Acolbifene (EM-652), the active metabolite of EM800, is an orally active pure antiestrogen and selective estrogen receptor antagonist.
  • HY-18719E
    Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity.
  • HY-103451
    Antagonist ≥99.0%
    (R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively.
  • HY-103454B
    MPP hydrochloride
    Modulator 99.58%
    MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator.
  • HY-132194
    ERα degrader-2
    Inhibitor 99.71%
    ERα degrader-2 is a selective estrogen receptor degrader (SERD) with potent binding affinity with ERα (IC50=17.1 nM), good degradation efficacy (EC50=0.3 nM).
  • HY-145341
    GNE-149 is an orally bioavailable full antagonist of estrogen receptor α (ERα; IC50=0.053 nM).
  • HY-114411
    ERRγ Inverse Agonist 1
    ERRγ Inverse Agonist 1 (Compound 12) is a potent, selective and orally bioavailable Estrogen-related Receptor grammar (ERRγ) inverse agonist, with an IC50 of 40 nM.
  • HY-146267
    ERα degrader 5
    ERα degrader 5 (Compound 40) is a selective, orally bioavailable estrogen receptor (ER) degrader (SERD) with an EC50 of 1.1 nM against ERα.
Cat. No. Product Name / Synonyms Species Source