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Smurf1-IN-A01 (Synonyms: A01)

Cat. No.: HY-110195
Handling Instructions

Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

For research use only. We do not sell to patients.

Smurf1-IN-A01 Chemical Structure

Smurf1-IN-A01 Chemical Structure

CAS No. : 1007647-73-5

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Description

Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3.664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation[1].

IC50 & Target

Kd: 3.664 nM (Smurf1)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

512.93

Formula

C₂₂H₂₀ClF₃N₄O₃S

CAS No.

1007647-73-5

SMILES

O=S(C1=CC(C(F)(F)F)=C(Cl)C=C1)(N2CCN(C(C3=CC=C(N4C(C)=CC=N4)C=C3)=O)CC2)=O

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Room temperature in continental US; may vary elsewhere

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Product Name:
Smurf1-IN-A01
Cat. No.:
HY-110195
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Smurf1-IN-A01

Cat. No.: HY-110195