1. Signaling Pathways
  2. Others
  3. Estrogen Receptor/ERR
  4. ERβ Isoform

ERβ

 
Cat. No. Product Name Effect Purity
  • HY-12452
    DPN
    Agonist 99.66%
    DPN (Diarylpropionitrile) is a non-steroidal estrogen receptor β (ERβ) selective ligand, with an EC50 of 0.85 nM.
  • HY-N0250
    Saikosaponin D
    Activator 98.76%
    Saikosaponin D is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.
  • HY-14933
    Prinaberel
    Agonist 98.05%
    Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively.
  • HY-B1662
    Hexestrol
    Agonist 99.88%
    Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ.
  • HY-103454
    MPP dihydrochloride
    Modulator 99.06%
    MPP dihydrochloride is a potent and selective ER (estrogen receptor) modulator.
  • HY-103451
    (R,R)-THC
    Antagonist
    (R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively.
  • HY-146267
    ERα degrader 5
    Antagonist
    ERα degrader 5 (Compound 40) is a selective, orally bioavailable estrogen receptor (ER) degrader (SERD) with an EC50 of 1.1 nM against ERα.
  • HY-103446
    FERb 033
    Agonist
    FERb 033 is a selective and potent ERβ agonist (Ki=7.1 nM, EC50=4.8 nM).
  • HY-18295
    Erteberel
    Agonist ≥99.0%
    Erteberel (LY500307) is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively.
  • HY-16023
    Acolbifene hydrochloride
    Antagonist 98.48%
    Acolbifene (EM-652) hydrochloride, an active metabolite of EM800, is an orally active, cancer-preventing selective estrogen receptor modulator (SERM).
  • HY-125263
    OP-1074
    Inhibitor 99.47%
    OP-1074 is a pure antiestrogen and a selective ER degrader (PA-SERD), shows specific antiestrogenic activity for ERα and ERβ, inhibits 17β-estradiol (E2)-stimulated transcriptional activity with IC50 of 1.6 and 3.2 nM, respectively.
  • HY-16023A
    Acolbifene
    Antagonist 98.86%
    Acolbifene (EM-652), the active metabolite of EM800, is an orally active pure antiestrogen and selective estrogen receptor antagonist.
  • HY-150693
    Estrogen receptor β antagonist 2
    Antagonist
    Estrogen receptor β antagonist 2 is a potent and selective estrogen receptor β (ERβ) antagonist with IC50s of 109.10, 0.63 µM for Erα and Erβ, respectively.
  • HY-125703
    Ferutinin
    Modulator
    Ferutinin, a natural terpenoid compound, is an estrogen receptor ERα agonist and estrogen ERβ-receptor agonist/antagonist with IC50s of 33.1 nM and 180.5 nM, respectively.
  • HY-110157
    AC-186
    Agonist
    AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively.
  • HY-110392
    CMP8
    CMP8, a selective ligand for estrogen receptor, binds to the mutant estrogen receptor ligand binding domain (ERLBD).
  • HY-103457
    Y134
    Antagonist
    Y134 is a selective and orally active oestrogen receptor (ER) modulator (SERM), exhibits potent antagonist activity at ERα and ERβ.
  • HY-N6052
    (+)-Medicarpin
    Activator
    (+)-Medicarpin, a pterocarpan, is a type of isoflavonoid isolated from several medicinal plant species with various biological effects, including Sophora japonica, Zollernia paraensis and Platymiscium yucatamun, Machaerium aristulatum, Platymiscium floribundum, and so on.
  • HY-150601
    Estrogen receptor-IN-1
    Inhibitor
    Estrogen receptor-IN-1 (compound 16) is a potent estrogen receptor (ER) inhibitor with IC50s of 13, 5µM for ERα and Erβ, respectively.
  • HY-138690
    Estrogen receptor modulator 6
    Agonist
    Estrogen receptor modulator 6 (compound 3a) is a selective estrogen receptor (ER) β agonist (Ki=0.44 nM).
Cat. No. Product Name / Synonyms Species Source